日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reticulocyte mitochondrial retention increases reactive oxygen species and oxygen consumption in mouse models of sickle cell disease and phlebotomy-induced anemia

网织红细胞线粒体滞留会增加镰状细胞病和放血诱发贫血的小鼠模型中的活性氧和氧消耗

Anne Gallivan, Mikail Alejandro, Amarachi Kanu, Nebeyat Zekaryas, Hart Horneman, Lenny K Hong, Elliott Vinchinsky, Don Lavelle, Alan M Diamond, Robert E Molokie, Jagadeesh Ramasamy, Angela Rivers

Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease

药理学抑制 LSD1 和 mTOR 可降低镰状细胞病红细胞中的线粒体滞留和相关 ROS 水平

Ramasamy Jagadeeswaran, Benjamin A Vazquez, Muthusamy Thiruppathi, Balaji B Ganesh, Vinzon Ibanez, Shuaiying Cui, James D Engel, Alan M Diamond, Robert E Molokie, Joseph DeSimone, Donald Lavelle, Angela Rivers

The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis)

LSD1 抑制剂 RN-1 重现了狒狒(P. anubis)胎儿时期的血红蛋白合成模式

Angela Rivers, Kestis Vaitkus, Vinzon Ibanez, Maria Armila Ruiz, Ramasamy Jagadeeswaran, Yogen Saunthararajah, Shuaiying Cui, James D Engel, Joseph DeSimone, Donald Lavelle

Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation

红系分化过程中羟甲基胞嘧啶和γ-珠蛋白基因启动子的去甲基化

Maria Armila Ruiz ,Angela Rivers, Vinzon Ibanez, Kestis Vaitkus, Nadim Mahmud, Joseph DeSimone, Donald Lavelle

RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model

RN-1 是一种强效且选择性的赖氨酸特异性脱甲基酶 1 抑制剂,可增加镰状细胞病小鼠模型中的 γ-珠蛋白表达、F 网织红细胞和 F 细胞

Angela Rivers, Kestis Vaitkus, Maria Armila Ruiz, Vinzon Ibanez, Ramasamy Jagadeeswaran, Tatiana Kouznetsova, Joseph DeSimone, Donald Lavelle

Simple prescribing errors and allergy documentation in medical hospital admissions in Australia and New Zealand

澳大利亚和新西兰医疗住院患者中简单的处方错误和过敏记录问题

Barton, Lorna; Futtermenger, Judith; Gaddi, Yash; Kang, Angela; Rivers, Jon; Spriggs, David; Jenkins, Paul F; Thompson, Campbell H; Thomas, Josephine S