Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia
通过 BET 溴结构域抑制剂进行表观遗传调控作为治疗前颗粒蛋白缺乏型额颞叶痴呆的新策略
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-59110-7
Zachary C Rosenthal, Daniel M Fass, N Connor Payne, Angela She, Debasis Patnaik, Krista M Hennig, Rachel Tesla, Gordon C Werthmann, Charlotte Guhl, Surya A Reis, Xiaoyu Wang, Yueting Chen, Michael Placzek, Noelle S Williams, Jacob Hooker, Joachim Herz, Ralph Mazitschek, Stephen J Haggarty