日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nicotinamide phosphoribosyltransferase activates the mitochondrial unfolded protein response to promote pulmonary arterial endothelial cell proliferation.

烟酰胺磷酸核糖转移酶激活线粒体未折叠蛋白反应,促进肺动脉内皮细胞增殖。

Lockett Angelia D, Adogamhe Pontian, Snow Aaron, Gomes Marta T, Machado Roberto F

The mitochondrial unfolded protein response and metabolic reprogramming promote PASMC proliferation in response to sphingosine kinase-1/sphingosine-1-phosphate signaling.

线粒体未折叠蛋白反应和代谢重编程促进 PASMC 增殖,以响应鞘氨醇激酶-1/鞘氨醇-1-磷酸信号传导

Lockett Angelia D, Snow Aaron, Adogamhe Pontian, Sysol Justin, Yadav Manas, Mubuuke Tendo, Gomes Marta T, Cook Todd, Fisher Amanda, Aldred Micheala A, Machado Roberto F

High Levels of Triggering Receptor Expressed in Myeloid Cells-Like Transcript-1 Positive, but Not Glycoprotein 1b+, Microparticles Are Associated With Poor Outcomes in Acute Respiratory Distress Syndrome

髓系细胞中表达的高水平触发受体(样转录本-1 阳性,而非糖蛋白 1b+)微粒与急性呼吸窘迫综合征的不良预后相关

Angelia D Gibson, Zaida Bayrón-Marrero, Benjamin Nieves-Lopez, Gerónimo Maldonado-Martínez, A Valance Washington

Elastase alters contractility and promotes an inflammatory synthetic phenotype in airway smooth muscle tissues.

弹性蛋白酶可改变气道平滑肌组织的收缩性,并促进炎症合成表型

Lockett Angelia D, Wu Yidi, Gunst Susan J

Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure

补充α1-抗胰蛋白酶可改善吸烟后肺泡巨噬细胞的胞吞作用和吞噬作用

Serban, Karina A; Petrusca, Daniela N; Mikosz, Andrew; Poirier, Christophe; Lockett, Angelia D; Saint, Lauren; Justice, Matthew J; Twigg, Homer L 3rd; Campos, Michael A; Petrache, Irina

Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells

清道夫受体 B 类、I 型介导肺内皮细胞对 A1AT 的吸收

Angelia D Lockett, Daniela N Petrusca, Matthew J Justice, Christophe Poirier, Karina A Serban, Natalia I Rush, Malgorzata Kamocka, Dan Predescu, Sanda Predescu, Irina Petrache

Active trafficking of alpha 1 antitrypsin across the lung endothelium

α1-抗胰蛋白酶主动转运穿过肺内皮细胞

Lockett, Angelia D; Brown, Mary Beth; Santos-Falcon, Nieves; Rush, Natalia I; Oueini, Houssam; Oberle, Amber J; Bolanis, Esther; Fragoso, Miryam A; Petrusca, Daniela N; Serban, Karina A; Schweitzer, Kelly S; Presson, Robert G Jr; Campos, Michael; Petrache, Irina

Selective endothelin-A receptor blockade attenuates endotoxin-induced pulmonary hypertension and pulmonary vascular dysfunction

选择性内皮素A受体阻断可减轻内毒素诱导的肺动脉高压和肺血管功能障碍

Toney, Brent M; Fisher, Amanda J; Albrecht, Marjorie; Lockett, Angelia D; Presson, Robert G; Petrache, Irina; Lahm, Tim

α₁-Antitrypsin modulates lung endothelial cell inflammatory responses to TNF-α

α₁-抗胰蛋白酶调节肺内皮细胞对 TNF-α 的炎症反应

Angelia D Lockett, Samuel Kimani, Godfrey Ddungu, Sabine Wrenger, Rubin M Tuder, Sabina M Janciauskiene, Irina Petrache

Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases

香烟烟雾暴露和结构修饰对 α-1 抗胰蛋白酶与半胱天蛋白酶相互作用的影响

Angelia D Lockett, Mary Van Demark, Yuan Gu, Kelly S Schweitzer, Ninotchka Sigua, Krzysztof Kamocki, Iwona Fijalkowska, Jana Garrison, Amanda J Fisher, Karina Serban, Robert A Wise, Terence R Flotte, Christian Mueller, Robert G Presson Jr, Horia I Petrache, Rubin M Tuder, Irina Petrache