iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome
iPSC 衍生的神经元分析显示，GABA 能电路中断和乙酰化 α-微管蛋白缺陷，而雷特综合征患者接受 iHDAC6 治疗后症状有所改善
期刊:Experimental Cell Research
影响因子:3.3
doi:10.1016/j.yexcr.2018.05.001
Elisa Landucci, Margherita Brindisi, Laura Bianciardi, Lorenza M Catania, Sergio Daga, Susanna Croci, Elisa Frullanti, Chiara Fallerini, Stefania Butini, Simone Brogi, Simone Furini, Riccardo Melani, Angelo Molinaro, Flaminia Clelia Lorenzetti, Valentina Imperatore, Sonia Amabile, Jessica Mariani, F
