C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation
抑制PKA或增强蛋白质降解的小分子可降低C9orf72 ALS/FTD二肽重复蛋白的水平
期刊:EMBO Journal
影响因子:9.4
doi:10.15252/embj.2020105026
Nausicaa V Licata, Riccardo Cristofani, Sally Salomonsson, Katherine M Wilson, Liam Kempthorne, Deniz Vaizoglu, Vito G D'Agostino, Daniele Pollini, Rosa Loffredo, Michael Pancher, Valentina Adami, Paola Bellosta, Antonia Ratti, Gabriella Viero, Alessandro Quattrone, Adrian M Isaacs, Angelo Poletti,