日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Smac-mimetic enhances antitumor effect of standard chemotherapy in ovarian cancer models via Caspase 8-independent mechanism

Smac 类似物通过 Caspase 8 非依赖机制增强卵巢癌模型中标准化疗的抗肿瘤作用

Lidia F Hernandez, Angie B Dull, Soumya Korrapati, Christina M Annunziata

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide

ATR 抑制可逆转同源重组缺陷型 MGMTlow/MMRproficient 癌细胞对替莫唑胺的耐药性

Lara H El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B Dull, Deborah F Wilsker, Melinda G Hollingshead, Michelle Gottholm-Ahalt, Sergio Y Alcoser, Michael E Mullendore, Ralph E Parchment, James H Doroshow, Beverly A Teicher, Annamaria Rapisarda

Evaluation of Pharmacodynamic Responses to Cancer Therapeutic Agents Using DNA Damage Markers

使用 DNA 损伤标记物评估癌症治疗剂的药效学反应

Deborah F Wilsker, Allison M Barrett, Angie B Dull, Scott M Lawrence, Melinda G Hollingshead, Alice Chen, Shivaani Kummar, Ralph E Parchment, James H Doroshow, Robert J Kinders

Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumor tissue and its application in distinguishing cytotoxic drug-induced DNA double strand breaks from DNA double strand breaks associated with apoptosis

建立固定肿瘤组织中细胞凋亡的定量药效学检测方法,并应用于区分细胞毒性药物引起的 DNA 双链断裂与与细胞凋亡相关的 DNA 双链断裂

Angie B Dull, Deborah Wilsker, Melinda Hollingshead, Christina Mazcko, Christina M Annunziata, Amy K LeBlanc, James H Doroshow, Robert J Kinders, Ralph E Parchment

Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro

通过高内涵筛选鉴定可诱导荧光雌激素受体 α 嵌合体从细胞质定位到细胞核并在体外表现出激动剂或拮抗剂活性的化合物

Angie B Dull, Anuja A George, Ekaterina I Goncharova, Jason R Evans, Antony Wamiru, Laura K Cartner, Gordon L Hager, James B McMahon

Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay

使用基于细胞的检测方法从 NCI 结构多样性库中鉴定四种潜在的表观遗传调节剂

Anne M Best, Jianjun Chang, Angie B Dull, John A Beutler, Elisabeth D Martinez