Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells
强效且选择性的 SETDB1 共价负变构调节剂可降低细胞中的甲基转移酶活性
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-57005-3
Mélanie Uguen, Devan J Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M Szewczyk, Ka Yang, Yani Zhao, Michael A Stashko, Jacqueline L Norris-Drouin, Jarod M Waybright, Serap Beldar, Justin M Rectenwald, Angie L Mordant, Thomas S Webb, Laura E Herring, Cheryl H Arrowsmith, Suzanne Ackloo, S