日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IGM-7354, an Immunocytokine with IL15 Fused to an Anti-PD-L1 IgM, Induces NK and CD8+ T cell-Mediated Cytotoxicity of PD-L1-Positive Tumor Cells

IGM-7354 是一种免疫细胞因子,其由 IL15 与抗 PD-L1 IgM 融合而成,可诱导 NK 细胞和 CD8+ T 细胞介导的对 PD-L1 阳性肿瘤细胞的细胞毒性。

Mélanie Desbois ,Thierry Giffon ,Poonam Yakkundi ,Carolyn R Denson ,Keerthana Sekar ,Kevin C Hart ,Daniel Santos ,Susan E Calhoun ,Kathryn Logronio ,Sivani Pandey ,Dean Ng ,Avneesh K Saini ,Beatrice T Wang ,Bruce A Keyt ,Angus M Sinclair ,Maya F Kotturi

Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199

多聚抗 DR5 IgM 激动剂抗体 IGM-8444 是癌细胞凋亡的强效诱导剂,并与化疗和 BCL-2 抑制剂 ABT-199 产生协同作用

Beatrice T Wang, Tasnim Kothambawala #, Ling Wang #, Thomas J Matthew #, Susan E Calhoun, Avneesh K Saini, Maya F Kotturi, Genevive Hernandez, Eric W Humke, Marvin S Peterson, Angus M Sinclair, Bruce A Keyt

The Broad Anti-AML Activity of the CD33/CD3 BiTE Antibody Construct, AMG 330, Is Impacted by Disease Stage and Risk

CD33/CD3 BiTE 抗体构建体 AMG 330 的广泛抗 AML 活性受疾病阶段和风险的影响

Kimberly H Harrington, Chelsea J Gudgeon, George S Laszlo, Kathryn J Newhall, Angus M Sinclair, Stanley R Frankel, Roman Kischel, Guang Chen, Roland B Walter