日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A rapid RIG-I signaling relay mediates efficient antiviral response

快速 RIG-I 信号传递介导有效的抗病毒反应

Daniel T Thoresen, Drew Galls, Benjamin Götte, Wenshuai Wang, Anna M Pyle

A stem-loop RNA RIG-I agonist protects against acute and chronic SARS-CoV-2 infection in mice

茎环 RNA RIG-I 激动剂可预防小鼠急性和慢性 SARS-CoV-2 感染

Tianyang Mao, Benjamin Israelow, Carolina Lucas, Chantal B F Vogels, Maria Luisa Gomez-Calvo, Olga Fedorova, Mallery I Breban, Bridget L Menasche, Huiping Dong, Melissa Linehan; Yale SARS-CoV-2 Genome Surveillance Initiative; Craig B Wilen, Marie L Landry, Nathan D Grubaugh, Anna M Pyle, Akiko Iwasa

Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response

胰岛的功能结构揭示了驱动第一阶段钙反应的第一反应细胞群。

Kravets, Vira; Dwulet, JaeAnn M; Schleicher, Wolfgang E; Hodson, David J; Davis, Anna M; Pyle, Laura; Piscopio, Robert A; Sticco-Ivins, Maura; Benninger, Richard K P

microRNA-122 amplifies hepatitis C virus translation by shaping the structure of the internal ribosomal entry site

microRNA-122 通过塑造内部核糖体进入位点的结构来扩增丙型肝炎病毒的翻译

Philipp Schult, Hanna Roth, Rebecca L Adams, Caroline Mas, Lionel Imbert, Christian Orlik, Alessia Ruggieri, Anna M Pyle, Volker Lohmann

Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers

具有治疗活性的 RIG-I 激动剂可诱导乳腺癌中的免疫原性肿瘤细胞杀伤

David L Elion, Max E Jacobson, Donna J Hicks, Bushra Rahman, Violeta Sanchez, Paula I Gonzales-Ericsson, Olga Fedorova, Anna M Pyle, John T Wilson, Rebecca S Cook

The SMAD3 transcription factor binds complex RNA structures with high affinity

SMAD3 转录因子以高亲和力结合复杂的 RNA 结构

Thayne H Dickey, Anna M Pyle

Hepatitis C virus RNA replication and virus particle assembly require specific dimerization of the NS4A protein transmembrane domain

丙型肝炎病毒 RNA 复制和病毒颗粒组装需要 NS4A 蛋白跨膜结构域的特定二聚化

Andrew Kohlway, Nathan Pirakitikulr, Francisco N Barrera, Olga Potapova, Donald M Engelman, Anna M Pyle, Brett D Lindenbach