An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues
MDM2 降解剂对 MDM2 过表达的急性淋巴细胞白血病细胞表现出强效细胞毒性,而对正常细胞/组织的毒性极小
期刊:Cancer Letters
影响因子:9.1
doi:10.1016/j.canlet.2024.217126
Tao Liu, Lubing Gu, Anna Mui, Zhongzhi Wu, Najah Albadari, Wei Li, Muxiang Zhou