日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Simplifying glycan monitoring of complex antigens such as the SARS-CoV-2 spike to accelerate vaccine development

简化 SARS-CoV-2 刺突蛋白等复杂抗原的糖基监测,以加速疫苗开发

Janelle Sauvageau, Izel Koyuturk, Frank St Michael, Denis Brochu, Marie-France Goneau, Ian Schoenhofen, Sylvie Perret, Alexandra Star, Anna Robotham, Arsalan Haqqani, John Kelly, Michel Gilbert, Yves Durocher

A glyco-engineering approach for site-specific conjugation to Fab glycans

一种用于与 Fab 聚糖进行位点特异性结合的糖工程方法

Maria L Jaramillo, Traian Sulea, Yves Durocher, Mauro Acchione, Melissa J Schur, Anna Robotham, John F Kelly, Marie-France Goneau, Alma Robert, Yuneivy Cepero-Donates, Michel Gilbert

Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages

免疫球蛋白可变结构域框架区对非规范域内二硫键的序列耐受性

Dae Young Kim, Hiba Kandalaft, Michael J Lowden, Qingling Yang, Martin A Rossotti, Anna Robotham, John F Kelly, Greg Hussack, Joseph D Schrag, Kevin A Henry, Jamshid Tanha

Isolation and characterization of a VHH targeting the Acinetobacter baumannii cell surface protein CsuA/B

针对鲍曼不动杆菌细胞表面蛋白 CsuA/B 的 VHH 的分离和表征

Eric K Lei, Shannon Ryan, Henk van Faassen, Mary Foss, Anna Robotham, Isabel Baltat, Kelly Fulton, Kevin A Henry, Wangxue Chen, Greg Hussack

Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells

在中国仓鼠卵巢细胞中生产可制造的 SARS-CoV-2 刺突病毒样颗粒的临床前评估

Sergio P Alpuche-Lazcano, Matthew Stuible, Bassel Akache, Anh Tran, John Kelly, Sabahudin Hrapovic, Anna Robotham, Arsalan Haqqani, Alexandra Star, Tyler M Renner, Julie Blouin, Jean-Sébastien Maltais, Brian Cass, Kai Cui, Jae-Young Cho, Xinyu Wang, Daria Zoubchenok, Renu Dudani, Diana Duque, Michae

Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX

氢-氘交换质谱揭示了针对 hCAIX 催化域的 mAb 的三种独特结合反应

Joey G Sheff, John F Kelly, Anna Robotham, Traian Sulea, Félix Malenfant, Denis L'Abbé, Mélanie Duchesne, Alex Pelletier, Jean Lefebvre, Andrea Acel, Marie Parat, Mylene Gosselin, Cunle Wu, Yves Fortin, Jason Baardsnes, Henk Van Faassen, Shannon Awrey, Shawn C Chafe, Paul C McDonald, Shoukat Dedhar,

A novel glycan modifies the flagellar filament proteins of the oral bacterium Treponema denticola

一种新型聚糖修饰口腔细菌齿密螺旋体鞭毛丝蛋白

Kurni Kurniyati, John F Kelly, Evgeny Vinogradov, Anna Robotham, Youbing Tu, Juyu Wang, Jun Liu, Susan M Logan, Chunhao Li

Production of α2,6-sialylated IgG1 in CHO cells

CHO 细胞中 α2,6-唾液酸化 IgG1 的产生

Céline Raymond, Anna Robotham, Maureen Spearman, Michael Butler, John Kelly, Yves Durocher

Evidence that biosynthesis of the second and third sugars of the archaellin Tetrasaccharide in the archaeon Methanococcus maripaludis occurs by the same pathway used by Pseudomonas aeruginosa to make a di-N-acetylated sugar

有证据表明,古菌 Methanococcus maripaludis 中古菌素四糖的第二和第三种糖的生物合成与铜绿假单胞菌用于制造双-N-乙酰化糖的途径相同

Sarah Siu, Anna Robotham, Susan M Logan, John F Kelly, Kaoru Uchida, Shin-Ichi Aizawa, Ken F Jarrell