Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized guinea pig assay
将计算机模拟心律失常风险检测与 tPKPD 模型相结合，预测麻醉豚鼠检测中的 QTc 间期延长
期刊:Toxicology and Applied Pharmacology
影响因子:3.3
doi:10.1016/j.taap.2020.114883
Pierre Morissette, Sebastian Polak, Anne Chain, Jin Zhai, John P Imredy, Mary Jo Wildey, Jeffrey Travis, Kevin Fitzgerald, Patrick Fanelli, Elisa Passini, Blanca Rodriguez, Frederick Sannajust, Christopher Regan
