日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PPARγ, a key modulator of metabolic reprogramming, stemness and chemoresistance associated with retrodifferentiation in human hepatocellular carcinomas

PPARγ是代谢重编程、干性和化疗耐药性的关键调节因子,与人类肝细胞癌的逆分化有关。

Yoann Daniel ,Claudine Rauch ,Lucille Moutaux ,Lise Desquilles ,Tifenn Le Charpentier ,Karim Fekir ,Luis Cano ,Daniel Catheline ,Servane Pierre ,Agnès Burel ,Camille Savary ,Catherine Ribault ,Claude Bendavid ,Bruno Clément ,Caroline Aninat ,Vincent Rioux ,Orlando Musso ,Bernard Fromenty ,Florian Cabillic # ,Anne Corlu #

Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression

分化 HepaRG™ 细胞中的脂质体介导基因转移:肝脏特异性功能的表达及其对细胞色素 P450 2D6 表达的应用

Manuel Vlach, Hugo Coppens-Exandier, Agnès Jamin, Mathieu Berchel, Julien Scaviner, Christophe Chesné, Tristan Montier, Paul-Alain Jaffrès, Anne Corlu, Pascal Loyer

Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells

DMSO 处理 HepaRG 细胞的转录和表观遗传后果

Hélène Dubois-Pot-Schneider, Caroline Aninat, Kathrin Kattler, Karim Fekir, Kathleen Jarnouen, Virginie Cerec, Denise Glaise, Abdulrahman Salhab, Gilles Gasparoni, Kubo Takashi, Seiichi Ishida, Jörn Walter, Anne Corlu

Retrodifferentiation of Human Tumor Hepatocytes to Stem Cells Leads to Metabolic Reprogramming and Chemoresistance

人类肿瘤肝细胞向干细胞的逆转分化导致代谢重编程和化学抗性

Karim Fekir, Hélène Dubois-Pot-Schneider, Romain Désert, Yoann Daniel, Denise Glaise, Claudine Rauch, Fabrice Morel, Bernard Fromenty, Orlando Musso, Florian Cabillic, Anne Corlu

Cytochrome P450 1A1/2, 2B6 and 3A4 HepaRG Cell-Based Biosensors to Monitor Hepatocyte Differentiation, Drug Metabolism and Toxicity

细胞色素 P450 1A1/2、2B6 和 3A4 HepaRG 细胞生物传感器用于监测肝细胞分化、药物代谢和毒性

Manuel Vlach, Nicolas Quesnot, Hélène Dubois-Pot-Schneider, Catherine Ribault, Yann Verres, Kilian Petitjean, Claudine Rauch, Fabrice Morel, Marie-Anne Robin, Anne Corlu, Pascal Loyer

TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors

在双能肝祖细胞分化过程中,TET 催化的 5-羟甲基化先于 HNF4A 启动子的选择

Pierre-Benoit Ancey, Szilvia Ecsedi, Marie-Pierre Lambert, Fazlur Rahman Talukdar, Marie-Pierre Cros, Denise Glaise, Diana Maria Narvaez, Veronique Chauvet, Zdenko Herceg, Anne Corlu, Hector Hernandez-Vargas

Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix

人类多能干细胞在人类肝祖细胞 HepaRG 衍生的脱细胞基质上的肝分化

Liisa K Kanninen, Pauliina Porola, Johanna Niklander, Melina M Malinen, Anne Corlu, Christiane Guguen-Guillouzo, Arto Urtti, Marjo L Yliperttula, Yan-Ru Lou

De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas

从头 HAPLN1 表达标志着 Wnt 诱导的干细胞和纤维生成网络导致侵袭性人类肝细胞癌

Sihem Mebarki, Romain Désert, Laurent Sulpice, Marie Sicard, Mireille Desille, Frédéric Canal, Hélène Dubois-Pot Schneider, Damien Bergeat, Bruno Turlin, Pascale Bellaud, Elise Lavergne, Rémy Le Guével, Anne Corlu, Christine Perret, Cédric Coulouarn, Bruno Clément, Orlando Musso

Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.

利用人类多能干细胞和HepaRG细胞生成功能性胆管细胞样细胞

Dianat Noushin, Dubois-Pot-Schneider Hélène, Steichen Clara, Desterke Christophe, Leclerc Philippe, Raveux Aurélien, Combettes Laurent, Weber Anne, Corlu Anne, Dubart-Kupperschmitt Anne

Hepatocyte-stellate cell cross-talk in the liver engenders a permissive inflammatory microenvironment that drives progression in hepatocellular carcinoma

肝脏中的肝细胞-星状细胞串扰产生了一种允许的炎症微环境,从而推动了肝细胞癌的进展

Cédric Coulouarn, Anne Corlu, Denise Glaise, Isabelle Guénon, Snorri S Thorgeirsson, Bruno Clément