Anne E Kiltie相关文献与解析，生知库 | 链接生命科学的每一步

Juri Na ,Joseph A Newman ,Chee Kin Then ,Junetha Syed ,Iolanda Vendrell ,Ignacio Torrecilla ,Sophie Ellermann ,Kristijan Ramadan ,Roman Fischer ,Anne E Kiltie

细胞生物学

肿瘤免疫

肿瘤

发表日期：2021

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p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation

p97/VCP 抑制导致过度的 MRE11 依赖性 DNA 末端切除，从而促进电离辐射后的细胞死亡

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2021.109153

Susan Kilgas, Abhay Narayan Singh, Salome Paillas, Chee-Kin Then, Ignacio Torrecilla, Judith Nicholson, Lisa Browning, Iolanda Vendrell, Rebecca Konietzny, Benedikt M Kessler, Anne E Kiltie, Kristijan Ramadan

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

蛋白酶 SPRTN 和 SUMOylation 协调 DNA-蛋白质交联修复，以防止基因组不稳定

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2021.110080

Annamaria Ruggiano, Bruno Vaz, Susan Kilgas, Marta Popović, Gonzalo Rodriguez-Berriguete, Abhay N Singh, Geoff S Higgins, Anne E Kiltie, Kristijan Ramadan

信号转导

发表日期：2021

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p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation

p97/VCP抑制导致MRE11依赖性DNA末端切除过度，从而促进电离辐射后的细胞死亡

期刊:

影响因子:7.5

doi:PMC8170441

Susan Kilgas，Abhay Narayan Singh，Salome Paillas，Chee-Kin Then，Ignacio Torrecilla，Judith Nicholson，Lisa Browning，Iolanda Vendrell，Rebecca Konietzny，Benedikt M Kessler，Anne E Kiltie，Kristijan Ramadan

Irradiation at Ultra-High (FLASH) Dose Rates Reduces Acute Normal Tissue Toxicity in the Mouse Gastrointestinal System

超高剂量率 (FLASH) 辐射可降低小鼠胃肠系统中的急性正常组织毒性

期刊:International Journal of Radiation Oncology Biology Physics

影响因子:6.4

doi:10.1016/j.ijrobp.2021.08.004

Jia-Ling Ruan, Carl Lee, Shari Wouters, Iain D C Tullis, Mieke Verslegers, Mohamed Mysara, Chee Kin Then, Sean C Smart, Mark A Hill, Ruth J Muschel, Amato J Giaccia, Borivoj Vojnovic, Anne E Kiltie, Kristoffer Petersson

Ultrasound-Mediated Gemcitabine Delivery Reduces the Normal-Tissue Toxicity of Chemoradiation Therapy in a Muscle-Invasive Bladder Cancer Model

超声介导的吉西他滨输送可降低肌层浸润性膀胱癌模型中放化疗对正常组织的毒性

期刊:International Journal of Radiation Oncology Biology Physics

影响因子:6.4

doi:10.1016/j.ijrobp.2020.11.046

Jia-Ling Ruan, Richard J Browning, Yesna O Yildiz, Michael Gray, Luca Bau, Sukanta Kamila, James Thompson, Amy Elliott, Sean Smart, Anthony P McHale, John F Callan, Borivoj Vojnovic, Eleanor Stride, Anne E Kiltie

Evaluation of Loading Strategies to Improve Tumor Uptake of Gemcitabine in a Murine Orthotopic Bladder Cancer Model Using Ultrasound and Microbubbles

使用超声波和微泡评估小鼠原位膀胱癌模型中改善肿瘤对吉西他滨摄取的加载策略

期刊:Ultrasound in Medicine and Biology

影响因子:2.4

doi:10.1016/j.ultrasmedbio.2021.02.001

Jia-Ling Ruan, Richard J Browning, Yesna O Yildiz, Luca Bau, Sukanta Kamila, Michael D Gray, Lisa Folkes, Alix Hampson, Anthony P McHale, John F Callan, Borivoj Vojnovic, Anne E Kiltie, Eleanor Stride

Immunofluorescence microscopy-based detection of ssDNA foci by BrdU in mammalian cells

基于免疫荧光显微镜检测哺乳动物细胞中 BrdU 的 ssDNA 焦点

期刊:STAR Protocols

影响因子:1.3

doi:10.1016/j.xpro.2021.100978

Susan Kilgas, Anne E Kiltie, Kristijan Ramadan

The Histone Deacetylase Inhibitor Romidepsin Spares Normal Tissues While Acting as an Effective Radiosensitizer in Bladder Tumors in Vivo

组蛋白去乙酰化酶抑制剂罗米地辛在体内作为膀胱肿瘤的有效放射增敏剂的同时不伤害正常组织

期刊:International Journal of Radiation Oncology Biology Physics

影响因子:6.4

doi:10.1016/j.ijrobp.2020.01.015

Salome Paillas, Chee K Then, Susan Kilgas, Jia-Ling Ruan, James Thompson, Amy Elliott, Sean Smart, Anne E Kiltie

Association of Bacteroides acidifaciens relative abundance with high-fibre diet-associated radiosensitisation

酸化拟杆菌相对丰度与高纤维饮食相关放射增敏的关系

期刊:BMC Biology

影响因子:4.4

doi:10.1186/s12915-020-00836-x

Chee Kin Then #, Salome Paillas #, Xuedan Wang, Alix Hampson, Anne E Kiltie

微生物学

发表日期：2020

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SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells

SPRTN蛋白酶切割的MRE11会降低DNA修复能力并增强癌细胞的放射敏感性。

p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation

p97/VCP 抑制导致过度的 MRE11 依赖性 DNA 末端切除，从而促进电离辐射后的细胞死亡

The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

蛋白酶 SPRTN 和 SUMOylation 协调 DNA-蛋白质交联修复，以防止基因组不稳定

p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation

p97/VCP抑制导致MRE11依赖性DNA末端切除过度，从而促进电离辐射后的细胞死亡

Irradiation at Ultra-High (FLASH) Dose Rates Reduces Acute Normal Tissue Toxicity in the Mouse Gastrointestinal System

超高剂量率 (FLASH) 辐射可降低小鼠胃肠系统中的急性正常组织毒性

Ultrasound-Mediated Gemcitabine Delivery Reduces the Normal-Tissue Toxicity of Chemoradiation Therapy in a Muscle-Invasive Bladder Cancer Model

超声介导的吉西他滨输送可降低肌层浸润性膀胱癌模型中放化疗对正常组织的毒性

Evaluation of Loading Strategies to Improve Tumor Uptake of Gemcitabine in a Murine Orthotopic Bladder Cancer Model Using Ultrasound and Microbubbles

使用超声波和微泡评估小鼠原位膀胱癌模型中改善肿瘤对吉西他滨摄取的加载策略

Immunofluorescence microscopy-based detection of ssDNA foci by BrdU in mammalian cells

基于免疫荧光显微镜检测哺乳动物细胞中 BrdU 的 ssDNA 焦点

The Histone Deacetylase Inhibitor Romidepsin Spares Normal Tissues While Acting as an Effective Radiosensitizer in Bladder Tumors in Vivo

组蛋白去乙酰化酶抑制剂罗米地辛在体内作为膀胱肿瘤的有效放射增敏剂的同时不伤害正常组织

Association of Bacteroides acidifaciens relative abundance with high-fibre diet-associated radiosensitisation

酸化拟杆菌相对丰度与高纤维饮食相关放射增敏的关系