Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
Torin2 利用复制和检查点漏洞导致 PI3K 激活的三阴性乳腺癌细胞死亡
期刊:Cell Systems
影响因子:9
doi:10.1016/j.cels.2019.11.001
Sameer S Chopra, Anne Jenney, Adam Palmer, Mario Niepel, Mirra Chung, Caitlin Mills, Sindhu Carmen Sivakumaren, Qingsong Liu, Jia-Yun Chen, Clarence Yapp, John M Asara, Nathanael S Gray, Peter K Sorger
信号转导
细胞生物学
肿瘤
乳腺癌
肿瘤细胞
IHC
IP
WB
Checkpoint
PI3K/Akt
RFA2