日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gastrulation-stage gene expression in Nipbl+/- mouse embryos foreshadows the development of syndromic birth defects

Nipbl+/- 小鼠胚胎中原肠胚阶段基因的表达预示着综合征性出生缺陷的发展

Stephenson Chea, Jesse Kreger, Martha E Lopez-Burks, Adam L MacLean, Arthur D Lander, Anne L Calof

NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation

NTR 2.0:一种合理设计的前体药物转化酶,可显著提高靶向细胞消融的功效

Abigail V Sharrock #, Timothy S Mulligan #, Kelsi R Hall, Elsie M Williams, David T White, Liyun Zhang, Kevin Emmerich, Frazer Matthews, Saumya Nimmagadda, Selena Washington, Katherine D Le, Danielle Meir-Levi, Olivia L Cox, Meera T Saxena, Anne L Calof, Martha E Lopez-Burks, Arthur D Lander, Ding D

Decreasing Wapl dosage partially corrects embryonic growth and brain transcriptome phenotypes in Nipbl+/- embryos

降低 Wapl 剂量可部分纠正 Nipbl+/- 胚胎中的胚胎生长和脑转录组表型

Connor M Kean, Christopher J Tracy, Apratim Mitra, Beenish Rahat, Matthew T Van Winkle, Claudia M Gebert, Jacob A Noeker, Anne L Calof, Arthur D Lander, Judith A Kassis, Karl Pfeifer

Novel factor in olfactory ensheathing cell-astrocyte crosstalk: Anti-inflammatory protein α-crystallin B

嗅鞘细胞-星形胶质细胞串扰中的新因素:抗炎蛋白 α-晶体蛋白 B

Aybike Saglam, Anne L Calof, Susan Wray

The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome

Nipped-B 样 (Nipbl) 单倍体不足对全基因组黏连蛋白结合和靶基因表达的影响:模拟 Cornelia de Lange 综合征

Daniel A Newkirk #, Yen-Yun Chen #, Richard Chien #, Weihua Zeng, Jacob Biesinger, Ebony Flowers, Shimako Kawauchi, Rosaysela Santos, Anne L Calof, Arthur D Lander, Xiaohui Xie, Kyoko Yokomori

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome

在 Cornelia de Lange 综合征小鼠模型中,Nipbl 的减少会损害局部黏连蛋白的加载并影响转录,但不影响黏连依赖性功能

Silvia Remeseiro, Ana Cuadrado, Shimako Kawauchi, Anne L Calof, Arthur D Lander, Ana Losada

Cohesin mediates chromatin interactions that regulate mammalian β-globin expression

黏连蛋白介导染色质相互作用,调节哺乳动物 β-珠蛋白的表达

Richard Chien, Weihua Zeng, Shimako Kawauchi, M A Bender, Rosaysela Santos, Heather C Gregson, John A Schmiesing, Daniel A Newkirk, Xiangduo Kong, Alexander R Ball Jr, Anne L Calof, Arthur D Lander, Mark T Groudine, Kyoko Yokomori

Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue

卵泡抑素调节 BMP 自调节回路,以控制发育中的舌头中感觉域的大小和模式

Crestina L Beites, Piper L W Hollenbeck, Joon Kim, Robin Lovell-Badge, Arthur D Lander, Anne L Calof