MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL
MCL-1 是 B 细胞发育过程中所必需的,其缺失使特定 B 细胞亚群对 BCL-2 或 BCL-XL 的抑制敏感
期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/cddis.2016.237
Ingela B Vikström, Anne Slomp, Emma M Carrington, Laura M Moesbergen, Catherine Chang, Gemma L Kelly, Stefan P Glaser, J H Marco Jansen, Jeanette H W Leusen, Andreas Strasser, David C S Huang, Andrew M Lew, Victor Peperzak, David M Tarlinton