Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding
抗 HIV-1 广谱中和抗体 2F5 的互补决定区 H3 顶端消融可消除中和能力,但不影响核心表位结合
期刊:Journal of Virology
影响因子:4
doi:10.1128/JVI.02357-09
Jean-Philippe Julien, Nerea Huarte, Rubén Maeso, Stefka G Taneva, Annie Cunningham, José L Nieva, Emil F Pai