A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8(+) infiltration in glioma.
一项评估 PCSK9 抑制剂 evolocumab 对胶质瘤中肿瘤 MHC-I 表达和 CD8(+) 浸润影响的手术机会窗口试验。
期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-21064-9
Singh Kirit, Foster Matthew W, Violette Marlene J, Corcoran Anna M, Hotchkiss Kelly M, Railton Chelsea O, Blandford Emily E, Blethen Kathryn E, Thomas Elizabeth L, McIntosh William C, Ashley David M, Desjardins Annick, Friedman Henry S, Johnson Margaret O, Friedman Allan, Keir Stephen, Buckley Evan D, Herndon James E, McLendon Roger E, Sampson John H, Calabrese Evan, López Giselle Y, Grant Gerald A, Patel Anoop P, Gregory Simon G, Li Chuan-Yuan, Fecci Peter E, Khasraw Mustafa