日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Novel Natural Siderophore Antibiotic Conjugate Reveals a Chemical Approach to Macromolecule Coupling

一种新型天然铁载体抗生素偶联物揭示了大分子偶联的化学方法

Caradec, Thibault; Anoz-Carbonell, Ernesto; Petrov, Ravil; Billamboz, Muriel; Antraygues, Kevin; Cantrelle, Francois-Xavier; Boll, Emmanuelle; Beury, Delphine; Hot, David; Drobecq, Herve; Trivelli, Xavier; Hartkoorn, Ruben C

Protein-Energy Malnutrition Is Associated with Worse Outcomes in Patients with Atrial Fibrillation: A Nationwide Analysis

全国性分析显示,蛋白质能量营养不良与房颤患者预后不良相关。

Markson, Favour; Akuna, Emmanuel; Asemota, Iriagbonse; Areoye, Gabriel; Shahi, Anoz; Nwachukwu, Praise; Ong, Kenneth

Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis

辅因子和病原体:绵羊布鲁氏菌的FAD合成酶合成黄素单核苷酸和黄素腺嘌呤二核苷酸(FAD)。

Moreno, Andrea; Taleb, Victor; Sebastián, María; Anoz-Carbonell, Ernesto; Martínez-Júlvez, Marta; Medina, Milagros

Targeting HIF-1α Function in Cancer through the Chaperone Action of NQO1: Implications of Genetic Diversity of NQO1

通过 NQO1 的分子伴侣作用靶向 HIF-1α 在癌症中的功能:NQO1 遗传多样性的意义

Salido, Eduardo; Timson, David J; Betancor-Fernández, Isabel; Palomino-Morales, Rogelio; Anoz-Carbonell, Ernesto; Pacheco-García, Juan Luis; Medina, Milagros; Pey, Angel L

Allosteric Communication in the Multifunctional and Redox NQO1 Protein Studied by Cavity-Making Mutations

通过致腔突变研究多功能和氧化还原 NQO1 蛋白中的变构通讯

Juan Luis Pacheco-Garcia, Dmitry S Loginov, Ernesto Anoz-Carbonell, Pavla Vankova, Rogelio Palomino-Morales, Eduardo Salido, Petr Man, Milagros Medina, Athi N Naganathan, Angel L Pey

Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue

多功能NAD(P)H:醌氧化还原酶1错义突变的多效性和特异性表型后果的结构基础及其药理学挽救

Juan Luis Pacheco-Garcia ,Ernesto Anoz-Carbonell ,Pavla Vankova ,Adithi Kannan ,Rogelio Palomino-Morales ,Noel Mesa-Torres ,Eduardo Salido ,Petr Man ,Milagros Medina ,Athi N Naganathan ,Angel L Pey

Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies

黄素蛋白抑制剂选择性靶向治疗人类和动物幽门螺杆菌属病原体:功效、协同作用、抗性和机制研究

Sandra Salillas, Juan José Galano-Frutos, Alejandro Mahía, Ritwik Maity, María Conde-Giménez, Ernesto Anoz-Carbonell, Helena Berlamont, Adrian Velazquez-Campoy, Eliette Touati, Uwe Mamat, Ulrich E Schaible, José A Gálvez, María D Díaz-de-Villegas, Freddy Haesebrouck, José A Aínsa, Javier Sancho

In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target

利用计算机模拟发现和生物学验证FAD合成酶配体,FAD合成酶是一种很有前景的新型抗菌靶点

Lans, Isaias; Anoz-Carbonell, Ernesto; Palacio-Rodríguez, Karen; Aínsa, José Antonio; Medina, Milagros; Cossio, Pilar

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding

FAD 合酶异构体 6 中天冬氨酸 238 的突变通过削弱 FAD 结合来提高比活性

Piero Leone, Michele Galluccio, Stefano Quarta, Ernesto Anoz-Carbonell, Milagros Medina, Cesare Indiveri, Maria Barile

Discovery of antimicrobial compounds targeting bacterial type FAD synthetases

发现针对细菌型 FAD 合成酶的抗菌化合物

María Sebastián, Ernesto Anoz-Carbonell, Begoña Gracia, Pilar Cossio, José Antonio Aínsa, Isaías Lans, Milagros Medina