日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Small Molecule Activators of the Mitochondrial Protease ClpP Induce Senescence in Triple-Negative Breast Cancer Cells and Sensitize Cells to the Bcl-2 Inhibitor Venetoclax

线粒体蛋白酶ClpP的小分子激活剂可诱导三阴性乳腺癌细胞衰老,并使细胞对Bcl-2抑制剂维奈托克敏感。

Daglish, Sabrina C D; Canterbury, Owen G; Graves, Paul R; Carter, Sarah A; Beese, Sydney M; Hynek, Maggie A; Mouery, Brandon L; Mistreanu, Andrei J; Bhatt, Aadra P; Tellez, Nestor; Butler, Mitchell T; Aponte-Collazo, Lucas J; Fennell, Emily M J; Herring, Laura E; Lyons, Scott; Mills, C Allie; Ashamalla, Hani; Iwanowicz, Edwin J; Morris, John P 4th; Bear, James E; Greer, Yoshimi Endo; Lipkowitz, Stanley; Graves, Lee M

Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer

多组学分析显示 ClpP 激活剂会破坏三阴性乳腺癌中的重要线粒体通路

Emily M J Fennell, Lucas J Aponte-Collazo, Wimal Pathmasiri, Blake R Rushing, Natalie K Barker, Megan C Partridge, Yuan-Yuan Li, Cody A White, Yoshimi E Greer, Laura E Herring, Stanley Lipkowitz, Susan C J Sumner, Edwin J Iwanowicz, Lee M Graves

Correction to "Mitochondrial Protease ClpP Is a Target for the Anticancer Compounds ONC201 and Related Analogues"

更正“线粒体蛋白酶ClpP是抗癌化合物ONC201及其类似物的靶点”

Graves, Paul R; Aponte-Collazo, Lucas J; Fennell, Emily M J; Graves, Adam C; Hale, Andrew E; Dicheva, Nedyalka; Herring, Laura E; Gilbert, Thomas S K; East, Michael P; McDonald, Ian M; Lockett, Matthew R; Ashamalla, Hani; Moorman, Nathaniel J; Karanewsky, Donald S; Iwanowicz, Edwin J; Holmuhamedov, Ekhson; Graves, Lee M

Cocaine-Induced Locomotor Activation Differs Across Inbred Mouse Substrains

可卡因诱导的运动激活在不同近交系小鼠亚系中存在差异

Gaines, Christiann H; Schoenrock, Sarah A; Farrington, Joseph; Lee, David F; Aponte-Collazo, Lucas J; Shaw, Ginger D; Miller, Darla R; Ferris, Martin T; Pardo-Manuel de Villena, Fernando; Tarantino, Lisa M

Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP

TR-107 的特性分析:一种新型的人类线粒体蛋白酶 ClpP 化学激活剂

Emily M J Fennell ,Lucas J Aponte-Collazo ,Joshua D Wynn ,Kristina Drizyte-Miller ,Elisa Leung ,Yoshimi Endo Greer ,Paul R Graves ,Andrew A Iwanowicz ,Hani Ashamalla ,Ekhson Holmuhamedov ,Henk Lang ,Donald S Karanewsky ,Channing J Der ,Walid A Houry ,Stanley Lipkowitz ,Edwin J Iwanowicz ,Lee M Graves

Lyn regulates creatine uptake in an imatinib-resistant CML cell line

Lyn 调节伊马替尼耐药 CML 细胞系的肌酸摄取

Denis O Okumu, Lucas J Aponte-Collazo, Brian J Dewar, Nathan J Cox, Michael P East, Katherine Tech, Ian M McDonald, Andrey P Tikunov, Ekhson Holmuhamedov, Jeffrey M Macdonald, Lee M Graves

Mitochondrial Protease ClpP is a Target for the Anticancer Compounds ONC201 and Related Analogues

线粒体蛋白酶 ClpP 是抗癌化合物 ONC201 及其相关类似物的靶标

Paul R Graves, Lucas J Aponte-Collazo, Emily M J Fennell, Adam C Graves, Andrew E Hale, Nedyalka Dicheva, Laura E Herring, Thomas S K Gilbert, Michael P East, Ian M McDonald, Matthew R Lockett, Hani Ashamalla, Nathaniel J Moorman, Donald S Karanewsky, Edwin J Iwanowicz, Ekhson Holmuhamedov, Lee M Gr