日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome

成人大脑中谱系特异性的三维基因组结构以及染色质相互作用组的神经发育变化

期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gkad798
Samir Rahman,Pengfei Dong,Pasha Apontes,Michael B Fernando,Roman Kosoy,Kayla G Townsley,Kiran Girdhar,Jaroslav Bendl,Zhiping Shao,Ruth Misir,Nadia Tsankova,Steven P Kleopoulos,Kristen J Brennand,John F Fullard,Panos Roussos
Human
神经科学
发育与干细胞
发表日期：2023
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Population-level variation in enhancer expression identifies disease mechanisms in the human brain

增强子表达的群体水平变化可识别人类大脑中的疾病机制

期刊:Nature Genetics
影响因子:31.7
doi:10.1038/s41588-022-01170-4
Pengfei Dong, Gabriel E Hoffman, Pasha Apontes, Jaroslav Bendl, Samir Rahman, Michael B Fernando, Biao Zeng, James M Vicari, Wen Zhang, Kiran Girdhar, Kayla G Townsley, Ruth Misir; CommonMind Consortium; Kristen J Brennand, Vahram Haroutunian, Georgios Voloudakis, John F Fullard, Panos Roussos
信号转导
Human
发表日期：2022
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The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease

阿尔茨海默病中皮质染色质可及性的三维图谱

期刊:Nature Neuroscience
影响因子:20
doi:10.1038/s41593-022-01166-7
Bendl, Jaroslav; Hauberg, Mads E; Girdhar, Kiran; Im, Eunju; Vicari, James M; Rahman, Samir; Fernando, Michael B; Townsley, Kayla G; Dong, Pengfei; Misir, Ruth; Kleopoulos, Steven P; Reach, Sarah M; Apontes, Pasha; Zeng, Biao; Zhang, Wen; Voloudakis, Georgios; Brennand, Kristen J; Nixon, Ralph A; Haroutunian, Vahram; Hoffman, Gabriel E; Fullard, John F; Roussos, Panos
阿尔茨海默症
发表日期：2022
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Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation

纹状体区室化和纹状体成熟过程中新转录因子的无偏鉴定

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.65979
Maria-Daniela Cirnaru, Sicheng Song, Kizito-Tshitoko Tshilenge, Chuhyon Corwin, Justyna Mleczko, Carlos Galicia Aguirre, Houda Benlhabib, Jaroslav Bendl, Pasha Apontes, John Fullard, Jordi Creus-Muncunill, Azadeh Reyahi, Ali M Nik, Peter Carlsson, Panos Roussos, Sean D Mooney, Lisa M Ellerby, Michel
信号转导
ICC
发表日期：2021
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Evolution of regulatory signatures in primate cortical neurons at cell-type resolution

灵长类皮层神经元调控特征的演化（细胞类型分辨率）

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2011884117
Kozlenkov, Alexey; Vermunt, Marit W; Apontes, Pasha; Li, Junhao; Hao, Ke; Sherwood, Chet C; Hof, Patrick R; Ely, John J; Wegner, Michael; Mukamel, Eran A; Creyghton, Menno P; Koonin, Eugene V; Dracheva, Stella
信号转导
细胞生物学
神经科学
发表日期：2020
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A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons

DNA（羟基）甲基化在人类抑制神经元表观遗传调控中的独特作用

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.aau6190
Alexey Kozlenkov, Junhao Li, Pasha Apontes, Yasmin L Hurd, William M Byne, Eugene V Koonin, Michael Wegner, Eran A Mukamel, Stella Dracheva
神经
Human
发表日期：2018
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DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin Users Shows Significant Difference between Genomic Contexts of Hyper- and Hypomethylation and a Younger Epigenetic Age

海洛因使用者前额叶皮层神经元的DNA甲基化谱分析显示，高甲基化和低甲基化的基因组背景存在显著差异，且表观遗传年龄更年轻。

期刊:Genes
影响因子:2.8
doi:10.3390/genes8060152
Kozlenkov, Alexey; Jaffe, Andrew E; Timashpolsky, Alisa; Apontes, Pasha; Rudchenko, Sergei; Barbu, Mihaela; Byne, William; Hurd, Yasmin L; Horvath, Steve; Dracheva, Stella
表观遗传
DNA甲基化
神经科学
Human
DNA甲基化
发表日期：2017
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Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline

在与年龄相关的胰岛素抵抗和IGF-1水平下降的模型中，中枢胰岛素样生长因子-1 (IGF-1) 可恢复全身胰岛素作用。

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.12415
Huffman, Derek M; Farias Quipildor, Gabriela; Mao, Kai; Zhang, Xueying; Wan, Junxiang; Apontes, Pasha; Cohen, Pinchas; Barzilai, Nir
代谢
IGF-1
免疫/内分泌
发表日期：2016
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Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

芒果苷能促进碳水化合物氧化，并能预防高脂饮食引起的代谢紊乱。

期刊:Diabetes
影响因子:7.5
doi:10.2337/db14-0006
Apontes, Pasha; Liu, Zhongbo; Su, Kai; Benard, Outhiriaradjou; Youn, Dou Y; Li, Xisong; Li, Wei; Mirza, Raihan H; Bastie, Claire C; Jelicks, Linda A; Pessin, Jeffrey E; Muzumdar, Radhika H; Sauve, Anthony A; Chi, Yuling
代谢
发表日期：2014
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Dual mode action of mangiferin in mouse liver under high fat diet

芒果苷在高脂饮食小鼠肝脏中的双重作用

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0090137
Jihyeon Lim, Zhongbo Liu, Pasha Apontes, Daorong Feng, Jeffrey E Pessin, Anthony A Sauve, Ruth H Angeletti, Yuling Chi
信号转导
WB
Mouse
发表日期：2014
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