日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

T follicular helper cells transiently unlock a plasticity state in germinal centre B cells during the humoral immune response.

在体液免疫反应过程中,滤泡辅助性T细胞可短暂地激活生发中心B细胞的可塑性状态。

Scourzic Laurianne, Izzo Franco, Teater Matt, Polyzos Alexander P, Cucereavii Lucretia, Chin Christopher R, Papin Antonin, Pinto Hugo B, Mlynarczyk Coraline, Tsialta Ioanna, Xia Min, Lidoski Abigail, Myers Robert M, Israel Eva M, Venturutti Leandro, Mackay Simon P, Hoehn Kenneth B, Skoultchi Arthur I, Béguelin Wendy, Stadtfeld Matthias, Chen Zhengming, Landau Dan A, Melnick Ari M, Apostolou Effie

MED1 IDR deacetylation controls stress responsive genes through RNA Pol II recruitment

MED1 IDR去乙酰化通过RNA聚合酶II的募集来调控应激反应基因。

Lin, Ran; Mo, Yan; Barrows, Douglas; Mei, Wenbin; Onikubo, Takashi; Sun, Jianfeng; Zhang, Zhiguo; Apostolou, Effie; Tavazoie, Sohail F; Roeder, Robert G

Three-dimensional regulatory hubs support oncogenic programs in glioblastoma

三维调控中心支持胶质母细胞瘤中的致癌程序

Breves, Sarah L; Di Giammartino, Dafne Campigli; Nicholson, James; Cirigliano, Stefano; Mahmood, Syed Raza; Lee, Uk Jin; Martinez-Fundichely, Alexander; Jungverdorben, Johannes; Singhania, Richa; Rajkumar, Sandy; Kirou, Raphael; Studer, Lorenz; Khurana, Ekta; Polyzos, Alexander; Fine, Howard A; Apostolou, Effie

Author Correction: ChromaFold predicts the 3D contact map from single-cell chromatin accessibility

作者更正:ChromaFold 通过单细胞染色质可及性预测 3D 接触图。

Gao, Vianne R; Yang, Rui; Das, Arnav; Luo, Renhe; Luo, Hanzhi; McNally, Dylan R; Karagiannidis, Ioannis; Rivas, Martin A; Wang, Zhong-Min; Barisic, Darko; Karbalayghareh, Alireza; Wong, Wilfred; Zhan, Yingqian A; Chin, Christopher R; Noble, William S; Bilmes, Jeff A; Apostolou, Effie; Kharas, Michael G; Béguelin, Wendy; Viny, Aaron D; Huangfu, Danwei; Rudensky, Alexander Y; Melnick, Ari M; Leslie, Christina S

Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion.

有丝分裂后转录激活和 3D 调控相互作用对黏连蛋白耗竭表现出位点和分化特异性敏感性

Lee UkJin, Laguillo-Diego Alejandra, Wong Wilfred, Ni Zhangli, Cheng Lingling, Li Jieru, Pelham-Webb Bobbie, Pertsinidis Alexandros, Leslie Christina, Apostolou Effie

3D enhancer-promoter interactions and multi-connected hubs: Organizational principles and functional roles

3D增强子-促进子相互作用和多连接枢纽:组织原则和功能角色

Uyehara, Christopher M; Apostolou, Effie

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture

组蛋白H1缺失通过破坏三维染色质结构驱动淋巴瘤的发生。

Yusufova, Nevin; Kloetgen, Andreas; Teater, Matt; Osunsade, Adewola; Camarillo, Jeannie M; Chin, Christopher R; Doane, Ashley S; Venters, Bryan J; Portillo-Ledesma, Stephanie; Conway, Joseph; Phillip, Jude M; Elemento, Olivier; Scott, David W; Béguelin, Wendy; Licht, Jonathan D; Kelleher, Neil L; Staudt, Louis M; Skoultchi, Arthur I; Keogh, Michael-Christopher; Apostolou, Effie; Mason, Christopher E; Imielinski, Marcin; Schlick, Tamar; David, Yael; Tsirigos, Aristotelis; Allis, C David; Soshnev, Alexey A; Cesarman, Ethel; Melnick, Ari M

Deciphering the Complexity of 3D Chromatin Organization Driving Lymphopoiesis and Lymphoid Malignancies

解读驱动淋巴细胞生成和淋巴恶性肿瘤的三维染色质组织的复杂性

Scourzic, Laurianne; Salataj, Eralda; Apostolou, Effie

Dynamic 3D Chromatin Reorganization during Establishment and Maintenance of Pluripotency

多能性建立和维持过程中动态的三维染色质重组

Pelham-Webb, Bobbie; Murphy, Dylan; Apostolou, Effie

Transcription factors: building hubs in the 3D space

转录因子:在三维空间中构建枢纽

Di Giammartino, Dafne Campigli; Polyzos, Alexander; Apostolou, Effie