日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations

ERAP1与强直性脊柱炎的关联是由常见基因型而非罕见单倍型组合造成的。

Roberts, Amity R; Appleton, Louise H; Cortes, Adrian; Vecellio, Matteo; Lau, Jonathan; Watts, Laura; Brown, Matthew A; Wordsworth, Paul

Mutations in Known Monogenic High Bone Mass Loci Only Explain a Small Proportion of High Bone Mass Cases

已知单基因高骨量位点的突变只能解释一小部分高骨量病例。

Gregson, Celia L; Wheeler, Lawrie; Hardcastle, Sarah A; Appleton, Louise H; Addison, Kathryn A; Brugmans, Marieke; Clark, Graeme R; Ward, Kate A; Paggiosi, Margaret; Stone, Mike; Thomas, Joegi; Agarwal, Rohan; Poole, Kenneth E S; McCloskey, Eugene; Fraser, William D; Williams, Eleanor; Bullock, Alex N; Davey Smith, George; Brown, Matthew A; Tobias, Jon H; Duncan, Emma L

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

强直性脊柱炎的主要组织相容性复合体关联十分复杂,并且涉及与ERAP1的进一步上位性作用。

Cortes, Adrian; Pulit, Sara L; Leo, Paul J; Pointon, Jenny J; Robinson, Philip C; Weisman, Michael H; Ward, Michael; Gensler, Lianne S; Zhou, Xiaodong; Garchon, Henri-Jean; Chiocchia, Gilles; Nossent, Johannes; Lie, Benedicte A; Førre, Øystein; Tuomilehto, Jaakko; Laiho, Kari; Bradbury, Linda A; Elewaut, Dirk; Burgos-Vargas, Ruben; Stebbings, Simon; Appleton, Louise; Farrah, Claire; Lau, Jonathan; Haroon, Nigil; Mulero, Juan; Blanco, Francisco J; Gonzalez-Gay, Miguel A; Lopez-Larrea, C; Bowness, Paul; Gaffney, Karl; Gaston, Hill; Gladman, Dafna D; Rahman, Proton; Maksymowych, Walter P; Crusius, J Bart A; van der Horst-Bruinsma, Irene E; Valle-Oñate, Raphael; Romero-Sánchez, Consuelo; Hansen, Inger Myrnes; Pimentel-Santos, Fernando M; Inman, Robert D; Martin, Javier; Breban, Maxime; Wordsworth, Bryan Paul; Reveille, John D; Evans, David M; de Bakker, Paul I W; Brown, Matthew A

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.

通过对免疫相关基因位点进行高密度基因分型,鉴定强直性脊柱炎的多个风险变异

Cortes Adrian, Hadler Johanna, Pointon Jenny P, Robinson Philip C, Karaderi Tugce, Leo Paul, Cremin Katie, Pryce Karena, Harris Jessica, Lee Seunghun, Joo Kyung Bin, Shim Seung-Cheol, Weisman Michael, Ward Michael, Zhou Xiaodong, Garchon Henri-Jean, Chiocchia Gilles, Nossent Johannes, Lie Benedicte A, Førre Øystein, Tuomilehto Jaakko, Laiho Kari, Jiang Lei, Liu Yu, Wu Xin, Bradbury Linda A, Elewaut Dirk, Burgos-Vargas Ruben, Stebbings Simon, Appleton Louise, Farrah Claire, Lau Jonathan, Kenna Tony J, Haroon Nigil, Ferreira Manuel A, Yang Jian, Mulero Juan, Fernandez-Sueiro Jose Luis, Gonzalez-Gay Miguel A, Lopez-Larrea Carlos, Deloukas Panos, Donnelly Peter, Bowness Paul, Gafney Karl, Gaston Hill, Gladman Dafna D, Rahman Proton, Maksymowych Walter P, Xu Huji, Crusius J Bart A, van der Horst-Bruinsma Irene E, Chou Chung-Tei, Valle-Oñate Raphael, Romero-Sánchez Consuelo, Hansen Inger Myrnes, Pimentel-Santos Fernando M, Inman Robert D, Videm Vibeke, Martin Javier, Breban Maxime, Reveille John D, Evans David M, Kim Tae-Hwan, Wordsworth Bryan Paul, Brown Matthew A

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

ERAP1与HLA-B27在强直性脊柱炎中的相互作用表明,肽链处理参与了HLA-B27在疾病易感性中的机制。

Evans, David M; Spencer, Chris C A; Pointon, Jennifer J; Su, Zhan; Harvey, David; Kochan, Grazyna; Oppermann, Udo; Dilthey, Alexander; Pirinen, Matti; Stone, Millicent A; Appleton, Louise; Moutsianas, Loukas; Leslie, Stephen; Wordsworth, Tom; Kenna, Tony J; Karaderi, Tugce; Thomas, Gethin P; Ward, Michael M; Weisman, Michael H; Farrar, Claire; Bradbury, Linda A; Danoy, Patrick; Inman, Robert D; Maksymowych, Walter; Gladman, Dafna; Rahman, Proton; Morgan, Ann; Marzo-Ortega, Helena; Bowness, Paul; Gaffney, Karl; Gaston, J S Hill; Smith, Malcolm; Bruges-Armas, Jacome; Couto, Ana-Rita; Sorrentino, Rosa; Paladini, Fabiana; Ferreira, Manuel A; Xu, Huji; Liu, Yu; Jiang, Lei; Lopez-Larrea, Carlos; Díaz-Peña, Roberto; López-Vázquez, Antonio; Zayats, Tetyana; Band, Gavin; Bellenguez, Céline; Blackburn, Hannah; Blackwell, Jenefer M; Bramon, Elvira; Bumpstead, Suzannah J; Casas, Juan P; Corvin, Aiden; Craddock, Nicholas; Deloukas, Panos; Dronov, Serge; Duncanson, Audrey; Edkins, Sarah; Freeman, Colin; Gillman, Matthew; Gray, Emma; Gwilliam, Rhian; Hammond, Naomi; Hunt, Sarah E; Jankowski, Janusz; Jayakumar, Alagurevathi; Langford, Cordelia; Liddle, Jennifer; Markus, Hugh S; Mathew, Christopher G; McCann, Owen T; McCarthy, Mark I; Palmer, Colin N A; Peltonen, Leena; Plomin, Robert; Potter, Simon C; Rautanen, Anna; Ravindrarajah, Radhi; Ricketts, Michelle; Samani, Nilesh; Sawcer, Stephen J; Strange, Amy; Trembath, Richard C; Viswanathan, Ananth C; Waller, Matthew; Weston, Paul; Whittaker, Pamela; Widaa, Sara; Wood, Nicholas W; McVean, Gilean; Reveille, John D; Wordsworth, B Paul; Brown, Matthew A; Donnelly, Peter

The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD)

与强直性脊柱炎相关的 16q 染色体区域包含候选基因肿瘤坏死因子受体 1 型相关死亡结构域 (TRADD)

Pointon, Jennifer J; Harvey, David; Karaderi, Tugce; Appleton, Louise H; Farrar, Claire; Stone, Millicent A; Sturrock, Roger D; Reveille, John D; Weisman, Michael H; Ward, Michael M; Brown, Matthew A; Wordsworth, B Paul

Investigating the genetic association between ERAP1 and ankylosing spondylitis

研究ERAP1与强直性脊柱炎之间的遗传关联

Harvey, David; Pointon, Jennifer J; Evans, David M; Karaderi, Tugce; Farrar, Claire; Appleton, Louise H; Sturrock, Roger D; Stone, Millicent A; Oppermann, Udo; Brown, Matthew A; Wordsworth, B Paul