日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting mGlyR with nanobodies for depression

利用纳米抗体靶向mGlyR治疗抑郁症

Laboute, Thibaut; Zucca, Stefano; Sial, Omar K; Sharma, Mansi; Brunori, Gloria; Singh, Shikha; Nageswar, K V; Peng, Haiyong; Rader, Christoph; Becker, Jérôme Aj; Le Merrer, Julie; Singh, Appu K; Martemyanov, Kirill A

Defective anterograde protein-trafficking contributes to endoplasmic reticulum-stress in a CLN1 disease model

在CLN1疾病模型中,前向蛋白质运输缺陷会导致内质网应激。

Nisha Plavelil,Abhilash P Appu,K C Gopal,Avisek Mondal,Neil Perkins,Anil B Mukherjee

Defective anterograde protein-trafficking contributes to endoplasmic reticulum-stress in a CLN1 disease model

在CLN1疾病模型中,前向蛋白质运输缺陷会导致内质网应激。

Nisha Plavelil ,Abhilash P Appu ,K C Gopal ,Avisek Mondal ,Neil Perkins ,Anil B Mukherjee

Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179

细胞外基质蛋白皮卡丘林与孤儿受体 GPR179 的光感受器突触组装结构

Dipak N Patil, Serena Pantalone, Yan Cao, Thibaut Laboute, Scott J Novick, Shikha Singh, Simone Savino, Silvia Faravelli, Francesca Magnani, Patrick R Griffin, Appu K Singh, Federico Forneris, Kirill A Martemyanov

Structural basis of AMPA receptor inhibition by trans-4-butylcyclohexane carboxylic acid

反式-4-丁基环己烷羧酸抑制AMPA受体的结构基础

Yelshanskaya, Maria V; Singh, Appu K; Narangoda, Chamali; Williams, Robin S B; Kurnikova, Maria G; Sobolevsky, Alexander I

Inactivation-mimicking block of the epithelial calcium channel TRPV6

模拟上皮钙通道 TRPV6 失活阻断

Rajesh Bhardwaj, Sonja Lindinger, Arthur Neuberger, Kirill D Nadezhdin, Appu K Singh, Micael R Cunha, Isabella Derler, Gergely Gyimesi, Jean-Louis Reymond, Matthias A Hediger, Christoph Romanin, Alexander I Sobolevsky

Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii

莱茵衣藻温敏 TRP 通道 TRP1 的结构

Luke L McGoldrick, Appu K Singh, Lusine Demirkhanyan, Ting-Yu Lin, Ryan G Casner, Eleonora Zakharian, Alexander I Sobolevsky

Structural basis of temperature sensation by the TRP channel TRPV3

TRP 通道 TRPV3 的温度感觉结构基础

Appu K Singh, Luke L McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian, Alexander I Sobolevsky

Opening of the human epithelial calcium channel TRPV6

人类上皮钙通道 TRPV6 的开放

Luke L McGoldrick, Appu K Singh, Kei Saotome, Maria V Yelshanskaya, Edward C Twomey, Robert A Grassucci, Alexander I Sobolevsky

Structure and gating mechanism of the transient receptor potential channel TRPV3

瞬时受体电位通道TRPV3的结构和门控机制

Appu K Singh, Luke L McGoldrick, Alexander I Sobolevsky