The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis
内质网应激传感器IRE1通过增强蛋白质稳态因子P4HB/PDIA1的活性来调节胶原蛋白分泌，从而导致肝损伤和纤维化。
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doi:10.1101/2023.05.02.538835
Hazari, Younis; Urra, Hery; Garcia Lopez, Valeria A; Diaz, Javier; Tamburini, Giovanni; Milani, Mateus; Pihan, Philippe; Durand, Sylvere; Aprahamia, Fanny; Baxter, Reese; Huang, Menghao; Dong, X Charlie; Vihinen, Helena; Batista-Gonzalez, Ana; Godoy, Patricio; Criollo, Alfredo; Ratziu, Vlad; Foufelle, Fabienne; Hengstler, Jan G; Jokitalo, Eija; Bailly-Maitre, Beatrice; Maiers, Jessica L; Plate, Lars; Kroemer, Guido; Hetz, Claudio
