日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immune Niche Formation Reveals Mechanisms of Tumor Dormancy and Targeting Opportunities.

免疫微环境的形成揭示了肿瘤休眠机制和靶向治疗机会。

Ahad Abdul, Leng Feng, Ichise Hiroshi, Schrom Edward, So Jae Young, Sellner Carter, Gu Yang, Wang Wenjuan, Kieu Celine, Park Woo Yong, Yang Rachel, Wolcott Karen, Livak Ferenc, Kruhlak Michael, Aprelikova Olga, Gray Justin, Kopardé Vishal N, Moriwaki Yasuhiro, Germain Ronald N, Yang Li

Immune Niche Formation in Engineered Mouse Models Reveals Mechanisms of Tumor Dormancy.

基因工程小鼠模型中免疫微环境的形成揭示了肿瘤休眠的机制

Ahad Abdul, Leng Feng, Ichise Hiroshi, Schrom Edward, So Jae Young, Sellner Carter, Gu Yang, Wang Wenjuan, Kieu Celine, Park Woo Yong, Yang Rachel, Wolcott Karen, Livak Ferenc, Kruhlak Michael, Aprelikova Olga, Gray Justin, Kopardé Vishal N, Moriwaki Yasuhiro, Germain Ronald N, Yang Li

The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis.

表观遗传修饰因子 JMJD6 在乳腺肿瘤中扩增,并与 c-Myc 协同作用,增强细胞转化、肿瘤进展和转移。

Aprelikova Olga, Chen Kenny, El Touny Lara H, Brignatz-Guittard Constance, Han Justin, Qiu Tinghu, Yang Howard H, Lee Maxwell P, Zhu Min, Green Jeffrey E

Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases

具有肺、肝和脑转移的乳腺癌基底细胞癌免疫功能移植模型的开发及临床前应用

Olga Aprelikova, Christine C Tomlinson, Mark Hoenerhoff, Julie A Hixon, Scott K Durum, Ting-Hu Qiu, Siping He, Sandra Burkett, Zi-Yao Liu, Steven M Swanson, Jeffrey E Green

Impact of ischemia and procurement conditions on gene expression in renal cell carcinoma

缺血和获取条件对肾细胞癌基因表达的影响

Liu, Nick W; Sanford, Thomas; Srinivasan, Ramaprasad; Liu, Jack L; Khurana, Kiranpreet; Aprelikova, Olga; Valero, Vladimir; Bechert, Charles; Worrell, Robert; Pinto, Peter A; Yang, Youfeng; Merino, Maria; Linehan, W Marston; Bratslavsky, Gennady

Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß

MDA-MB-231 三阴性乳腺癌细胞中 GATA3 的表达会诱导对 TGFβ 的生长抑制反应

Isabel M Chu, Wei-Chu Lai, Olga Aprelikova, Lara H El Touny, Hosein Kouros-Mehr, Jeffrey E Green

Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer

跨物种基因组和功能分析确定使用 CHK1 抑制剂和核苷酸还原酶抑制剂的联合疗法治疗三阴性乳腺癌

Christina N Bennett, Christine C Tomlinson, Aleksandra M Michalowski, Isabel M Chu, Dror Luger, Lara R Mittereder, Olga Aprelikova, James Shou, Helen Piwinica-Worms, Natasha J Caplen, Melinda G Hollingshead, Jeffrey E Green

Differential genetic expression in large versus small clear cell renal cell carcinoma: results from microarray analysis

大细胞与小细胞肾透明细胞癌的差异基因表达:微阵列分析结果

Bratslavsky, Gennady; Sanford, Thomas; Srinivasan, Ramaprasad; Aprelikova, Olga; Liu, Jack; Quezado, Martha; Merino, Maria; Linehan, W Marston

miRNA signature associated with outcome of gastric cancer patients following chemotherapy

miRNA特征与胃癌患者化疗后的预后相关

Kim, Chang Hee; Kim, Hark K; Rettig, R Luke; Kim, Joseph; Lee, Eunbyul T; Aprelikova, Olga; Choi, Il J; Munroe, David J; Green, Jeffrey E

Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response

黑色素瘤抗原-11抑制缺氧诱导因子脯氨酰羟化酶2并激活缺氧反应

Aprelikova, Olga; Pandolfi, Silvia; Tackett, Sean; Ferreira, Mark; Salnikow, Konstantin; Ward, Yvona; Risinger, John I; Barrett, J Carl; Niederhuber, John