日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic Subtyping and Phenotypic Characterization of the Immune Microenvironment and MYC/BCL2 Double Expression Reveal Heterogeneity in Diffuse Large B-cell Lymphoma

免疫微环境的遗传亚型和表型表征以及 MYC/BCL2 双表达揭示弥漫大 B 细胞淋巴瘤的异质性

Zijun Y Xu-Monette #, Li Wei #, Xiaosheng Fang #, Qingyan Au #, Harry Nunns #, Máté Nagy, Alexandar Tzankov, Feng Zhu, Carlo Visco, Govind Bhagat, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D Hsi, Fredrick B Hagemeister, Xiaoping Sun, Xin Han, Heounjeong Go, Maurilio Ponzoni, Andrés J M Fe

JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition

JAK2/IDH突变驱动的骨髓增生性肿瘤对联合靶向抑制疗法敏感

Anna Sophia McKenney ,Allison N Lau ,Amritha Varshini Hanasoge Somasundara ,Barbara Spitzer ,Andrew M Intlekofer ,Jihae Ahn ,Kaitlyn Shank ,Franck T Rapaport ,Minal A Patel ,Efthymia Papalexi ,Alan H Shih ,April Chiu ,Elizaveta Freinkman ,Esra A Akbay ,Mya Steadman ,Raj Nagaraja ,Katharine Yen ,Julie Teruya-Feldstein ,Kwok-Kin Wong ,Raajit Rampal ,Matthew G Vander Heiden ,Craig B Thompson ,Ross L Levine

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

黏连蛋白复合物在正常和恶性造血中的剂量依赖性作用

Aaron D Viny, Christopher J Ott, Barbara Spitzer, Martin Rivas, Cem Meydan, Efthymia Papalexi, Dana Yelin, Kaitlyn Shank, Jaime Reyes, April Chiu, Yevgeniy Romin, Vitaly Boyko, Swapna Thota, Jaroslaw P Maciejewski, Ari Melnick, James E Bradner, Ross L Levine

Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L

基质内皮细胞通过 TNF 相关因子 BAFF、APRIL 和 CD40L 与慢性淋巴细胞白血病细胞建立双向串扰

Montserrat Cols, Carolina M Barra, Bing He, Irene Puga, Weifeng Xu, April Chiu, Wayne Tam, Daniel M Knowles, Stacey R Dillon, John P Leonard, Richard R Furman, Kang Chen, Andrea Cerutti

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

跨膜激活剂 TACI 通过适配器 MyD88 激活 B 细胞,从而触发免疫球蛋白类别转换

Bing He, Raul Santamaria, Weifeng Xu, Montserrat Cols, Kang Chen, Irene Puga, Meimei Shan, Huabao Xiong, James B Bussel, April Chiu, Anne Puel, Jeanine Reichenbach, László Marodi, Rainer Döffinger, Julia Vasconcelos, Andrew Issekutz, Jens Krause, Graham Davies, Xiaoxia Li, Bodo Grimbacher, Alessandr

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

HIV-1 通过长距离细胞间导管靶向全身和肠道 B 细胞,逃避病毒特异性 IgG2 和 IgA 反应

Weifeng Xu, Paul A Santini, John S Sullivan, Bing He, Meimei Shan, Susan C Ball, Wayne B Dyer, Thomas J Ketas, Amy Chadburn, Leona Cohen-Gould, Daniel M Knowles, April Chiu, Rogier W Sanders, Kang Chen, Andrea Cerutti

Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF

病毒双链 RNA 通过涉及 BAFF 的先天 TLR3 通路激活上呼吸道粘膜 B 细胞,从而触发 Ig 类别转换

Weifeng Xu, Paul A Santini, Allysia J Matthews, April Chiu, Alessandro Plebani, Bing He, Kang Chen, Andrea Cerutti