Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function
抗抑郁药相关浓度的氯胺酮代谢物(2R,6R)-羟基去甲氯胺酮不会阻断NMDA受体功能。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1816071116
Lumsden, Eric W; Troppoli, Timothy A; Myers, Scott J; Zanos, Panos; Aracava, Yasco; Kehr, Jan; Lovett, Jacqueline; Kim, Sukhan; Wang, Fu-Hua; Schmidt, Staffan; Jenne, Carleigh E; Yuan, Peixiong; Morris, Patrick J; Thomas, Craig J; Zarate, Carlos A Jr; Moaddel, Ruin; Traynelis, Stephen F; Pereira, Edna F R; Thompson, Scott M; Albuquerque, Edson X; Gould, Todd D