日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-scale dependency and drug screens to characterize the therapeutic vulnerabilities of multiple myeloma with 1q

大规模依赖性研究和药物筛选,旨在明确1q多发性骨髓瘤的治疗弱点

Sklavenitis-Pistofidis, Romanos; Lightbody, Elizabeth D; Reidy, Mairead; Tsuji, Junko; Alberge, Jean-Baptiste; Aranha, Michelle P; Heilpern-Mallory, Daniel; Roweth, Harvey G; Huynh, Daisy; Chong, Stephen J F; Chung, Anna Y; Zhang, Jeremy; Hackett, Liam; Haradhvala, Nicholas J; Wu, Ting; Su, Nang K; Berrios, Brianna; Belkin, Saveliy; Dutta, Ankit K; Knudson, Ryan A; Brandt, Carolyn; Greipp, Patricia T; Davids, Matthew S; Papaioannou, Maria; Getz, Gad; Ghobrial, Irene M; Manier, Salomon

Deeper response predicts better outcomes in high-risk-smoldering-myeloma: results of the I-PRISM phase II clinical trial

更深层次的治疗反应预示着高危冒烟型多发性骨髓瘤患者更好的预后:I-PRISM II期临床试验结果

Nadeem, Omar; Aranha, Michelle P; Redd, Robert; Timonian, Michael; Magidson, Sophie; Lightbody, Elizabeth D; Alberge, Jean-Baptiste; Bertamini, Luca; Dutta, Ankit K; El-Khoury, Habib; Bustoros, Mark; Laubach, Jacob P; Bianchi, Giada; O'Donnell, Elizabeth; Wu, Ting; Tsuji, Junko; Anderson, Kenneth C; Getz, Gad; Trippa, Lorenzo; Richardson, Paul G; Sklavenitis-Pistofidis, Romanos; Ghobrial, Irene M

Single-cell RNA sequencing defines distinct disease subtypes and reveals hypo-responsiveness to interferon in asymptomatic Waldenstrom's Macroglobulinemia.

单细胞 RNA 测序定义了不同的疾病亚型,并揭示了无症状华氏巨球蛋白血症对干扰素的低反应性

Sklavenitis-Pistofidis Romanos, Konishi Yoshinobu, Heilpern-Mallory Daniel, Wu Ting, Tsakmaklis Nicholas, Aranha Michelle P, Hunter Zachary R, Ali Alaa K, Tsuji Junko, Haradhvala Nicholas J, Lightbody Elizabeth D, Towle Katherine, Hevenor Laura, Romee Rizwan, Briercheck Edward L, Smith Eric L, Liacos Christine-Ivy, Kastritis Efstathios, Dimopoulos Meletios A, Treon Steven P, Getz Gad, Ghobrial Irene M

Structure-guided design of a broadly cross-reactive multivalent group a streptococcal vaccine

基于结构的广谱交叉反应多价A群链球菌疫苗设计

Dale, James B; Aranha, Michelle P; Penfound, Thomas A; Salehi, Sanaz; Smith, Jeremy C

Design of Broadly Cross-Reactive M Protein-Based Group A Streptococcal Vaccines

基于广谱交叉反应性M蛋白的A群链球菌疫苗的设计

Aranha, Michelle P; Penfound, Thomas A; Salehi, Sanaz; Botteaux, Anne; Smeesters, Pierre; Dale, James B; Smith, Jeremy C

Cross-reactive immunogenicity of group A streptococcal vaccines designed using a recurrent neural network to identify conserved M protein linear epitopes

利用循环神经网络识别保守的M蛋白线性表位设计的A群链球菌疫苗的交叉反应免疫原性

Spencer, Jay A; Penfound, Tom; Salehi, Sanaz; Aranha, Michelle P; Wade, Lauren E; Agarwal, Rupesh; Smith, Jeremy C; Dale, James B; Baudry, Jerome

Structure-based group A streptococcal vaccine design: Helical wheel homology predicts antibody cross-reactivity among streptococcal M protein-derived peptides

基于结构的A群链球菌疫苗设计:螺旋轮同源性预测链球菌M蛋白衍生肽之间的抗体交叉反应性

Aranha, Michelle P; Penfound, Thomas A; Spencer, Jay A; Agarwal, Rupesh; Baudry, Jerome; Dale, James B; Smith, Jeremy C

Combining Three-Dimensional Modeling with Artificial Intelligence to Increase Specificity and Precision in Peptide-MHC Binding Predictions

结合三维建模和人工智能提高肽-MHC结合预测的特异性和精确度

Aranha, Michelle P; Jewel, Yead S M; Beckman, Robert A; Weiner, Louis M; Mitchell, Julie C; Parks, Jerry M; Smith, Jeremy C