日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tumor growth inhibition-overall survival modeling in non-small cell lung cancer: A case study from GEMSTONE-302

非小细胞肺癌肿瘤生长抑制-总生存期模型:来自 GEMSTONE-302 的案例研究

Sheng, Yucheng; Teng, Shu-Wen; Wang, Jingru; Wang, Hao; Tse, Archie N

A first-in-human phase 1 study of nofazinlimab, an anti-PD-1 antibody, in advanced solid tumors and in combination with regorafenib in metastatic colorectal cancer

一项针对晚期实体瘤以及与瑞戈非尼联合治疗转移性结直肠癌的诺法嗪利单抗(一种抗PD-1抗体)的首次人体I期研究

Day, Daphne; Park, John J; Coward, Jermaine; Markman, Ben; Lemech, Charlotte; Kuo, James C; Prawira, Amy; Brown, Michael P; Bishnoi, Sarwan; Kotasek, Dusan; Strother, R Matthew; Cosman, Rasha; Su, Rila; Ma, Yiding; Yue, Zenglian; Hu, Hui-Han; Wu, Rachel; Li, Peiqi; Tse, Archie N

Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer

CS-1008治疗转移性结直肠癌患者的I期影像学和药效学试验

Ciprotti, Marika; Tebbutt, Niall C; Lee, Fook-Thean; Lee, Sze-Ting; Gan, Hui K; McKee, David C; O'Keefe, Graeme J; Gong, Sylvia J; Chong, Geoffrey; Hopkins, Wendie; Chappell, Bridget; Scott, Fiona E; Brechbiel, Martin W; Tse, Archie N; Jansen, Mendel; Matsumura, Manabu; Kotsuma, Masakatsu; Watanabe, Rira; Venhaus, Ralph; Beckman, Robert A; Greenberg, Jonathan; Scott, Andrew M

90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1

90 kDa 热休克蛋白抑制剂通过耗竭 Chk1 和 Wee1 来消除 p53 缺失肿瘤细胞中拓扑异构酶 I 毒素诱导的 G2/M 检查点。

Tse, Archie N; Sheikh, Tahir N; Alan, Ho; Chou, Ting-Chao; Schwartz, Gary K

Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780

Aurora B 激酶通过磷酸化视网膜母细胞瘤蛋白的丝氨酸 780 位点来调节有丝分裂后内复制检查点。

Nair, Jayasree S; Ho, Alan L; Tse, Archie N; Coward, Jesse; Cheema, Haider; Ambrosini, Grazia; Keen, Nicholas; Schwartz, Gary K

AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

AZD7762 是一种新型检查点激酶抑制剂,可促进检查点废除并增强 DNA 靶向疗法

Sonya D Zabludoff, Chun Deng, Michael R Grondine, Adam M Sheehy, Susan Ashwell, Benjamin L Caleb, Stephen Green, Heather R Haye, Candice L Horn, James W Janetka, Dongfang Liu, Elizabeth Mouchet, Shannon Ready, Judith L Rosenthal, Christophe Queva, Gary K Schwartz, Karen J Taylor, Archie N Tse, Graem