日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell characterization of the gastrointestinal HIV reservoir reveals heterogeneous cellular phenotypes.

对胃肠道 HIV 病毒库的单细胞表征揭示了异质性细胞表型。

Peterson Jackson J, Chandel Shipra, James Katherine, Bennett Elizabeth S, Wu Vincent, White Cory H, Allard Brigitte, Clohosey Matthew, Whitaker Taylor, Baker Caroline, Pedersen Susan, Peery Anne F, Gay Cynthia L, Betts Michael R, Margolis David M, Archin Nancie M, Browne Edward P

Histone decrotonylation plays a distinct role in HIV latency

组蛋白去泛素化在HIV潜伏期中发挥着独特的作用

Li, Xiaoyi; Li, Dajiang; Tang, Yuyang; Nearing, Marie; Varco-Merth, Benjamin; Chen, Hongjie; Smith, Davey; Gianella, Sara; Archin, Nancie M; Okoye, Afam A; Dandekar, Satya; Margolis, David M; Chirasani, Venkat R; Gumpper, Ryan H; Jiang, Guochun

Aberrant DNA methylation of genes regulating CD4+ T cell HIV-1 reservoir in women with HIV

感染艾滋病毒的女性体内,调控CD4+ T细胞HIV-1储存库的基因存在异常DNA甲基化。

Ke Xu ,Xinyu Zhang ,Kesava Asam ,Bryan C Quach ,Grier P Page ,Deborah Konkle-Parker ,Claudia Martinez ,Cecile D Lahiri ,Elizabeth F Topper ,Mardge H Cohen ,Seble G Kassaye ,Jack DeHovitz ,Mark H Kuniholm ,Nancie M Archin ,Amir Valizadeh ,Phyllis C Tien ,Vincent C Marconi ,Dana B Hancock ,Eric O Johnson ,Bradley E Aouizerat

Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

整合复合物亚基12敲除克服了HIV潜伏逆转的转录阻滞

Carley N Gray ,Manickam Ashokkumar ,Derek H Janssens ,Jennifer L Kirchherr ,Brigitte Allard ,Emily Hsieh ,Terry L Hafer ,Nancie M Archin ,Edward P Browne ,Michael Emerman

A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency.

有针对性的 CRISPR 筛选发现 ETS1 是 HIV-1 潜伏期的调节因子

Ashokkumar Manickam, Hafer Terry L, Felton Abby, Archin Nancie M, Margolis David M, Emerman Michael, Browne Edward P

Correction for Raines et al., "Nanoparticle delivery of Tat synergizes with classical latency reversal agents to express HIV antigen targets"

对 Raines 等人的论文“纳米颗粒递送 Tat 与经典潜伏期逆转剂协同作用以表达 HIV 抗原靶点”的更正

Raines, Samuel L M; Falcinelli, Shane D; Peterson, Jackson J; Van Gulck, Ellen; Allard, Brigitte; Kirchherr, Jennifer; Vega, Jerel; Najera, Isabel; Boden, Daniel; Archin, Nancie M; Margolis, David M

The persistent pool of HIV-1-infected cells is formed episodically during untreated infection

HIV-1 感染细胞的持久池是在未经治疗的感染过程中偶尔形成的

Olivia D Council, Lynn Tyers, Matthew Moeser, Amy Sondgeroth, Ean Spielvogel, Brian D Richardson, Deelan Doolabh, Shuntai Zhou, Ann Emery, Nancie M Archin, Bonnie Shook-Sa, David M Margolis, Salim S Abdool Karim, Sergei Kosakovsky Pond, Nigel Garrett, Melissa-Rose Abrahams, Sarah B Joseph, Carolyn W

A simple phylogenetic approach to analyze hypermutated HIV proviruses reveals insights into their dynamics and persistence during antiretroviral therapy

利用简单的系统发育方法分析高突变型HIV前病毒,可以深入了解其在抗逆转录病毒治疗期间的动态变化和持续存在情况。

Shahid, Aniqa; Jones, Bradley R; Duncan, Maggie C; MacLennan, Signe; Dapp, Michael J; Kuniholm, Mark H; Aouizerat, Bradley; Archin, Nancie M; Gange, Stephen; Ofotokun, Igho; Fischl, Margaret A; Kassaye, Seble; Goldstein, Harris; Anastos, Kathryn; Joy, Jeffrey B; Brumme, Zabrina L

Meeting report: 38th international conference on antiviral research in Las Vegas, United States of America, March 17-21, 2025

会议报告:第38届国际抗病毒研究大会,美国拉斯维加斯,2025年3月17日至21日

Jordan, Robert; Archin, Nancie M; Cagno, Valeria; Feng, Joy Y; Guo, Haitao; Herrero, Lara J; Janeba, Zlatko; Meanwell, Nicholas A; Moffat, Jennifer; Neyts, Johan; Rocha-Pereira, Joana; Seley-Radtke, Kathie L; Sheahan, Timothy P; Spengler, Jessica R; Welch, Stephen R; Xie, Xuping; Zakaryan, Hovakim; Schang, Luis M; Durantel, David

BET degraders reveal BRD4 disruption of 7SK and P-TEFb is critical for effective reactivation of latent HIV in CD4+ T-cells

BET降解剂揭示BRD4对7SK和P-TEFb的破坏对于CD4+ T细胞中潜伏HIV的有效激活至关重要。

Anne-Marie W Turner ,Frances M Bashore ,Shane D Falcinelli ,Joshua A Fox ,Alana L Keller ,Anthony D Fenton ,Renee F Geyer ,Brigitte Allard ,Jennifer L Kirchherr ,Nancie M Archin ,Lindsey I James ,David M Margolis