日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacokinetics and Safety of Selumetinib Granule Formulation in Children With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas (SPRINKLE; phase I/II)

Selumetinib颗粒剂治疗有症状、无法手术的1型神经纤维瘤病相关丛状神经纤维瘤患儿的药代动力学和安全性研究(SPRINKLE;I/II期)

Hernáiz Driever, Pablo; Kordes, Uwe R; Brecht, Ines B; Saletti, Veronica; Fisher, Michael J; Doughton, Gail; Arefayene, Million; Rigazio, Anna; Lluch, Nuria; Llorente, Nereida; Diede, Scott J; Salvador, Hector

First-in-Human Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of BIIB091, an Oral BTK Inhibitor, in Healthy Adult Participants

在健康成年受试者中首次进行口服 BTK 抑制剂 BIIB091 单次和多次递增口服剂量的人体安全性、耐受性、药代动力学和药效学研究

Tsai, Hui-Hsin; Gu, Yi; Riester, Katherine; Chu, Sherman S; Bame, Eris; Arefayene, Million; Kam, Jeanelle L Y L; Coppell, Alexander; Hanna, Jerome; Hopkins, Brian T; Scaramozza, Matthew

Randomized Phase IIa Clinical Study of an Anti-α(v)β(6) Monoclonal Antibody in Idiopathic Pulmonary Fibrosis

抗α(v)β(6)单克隆抗体治疗特发性肺纤维化的随机IIa期临床研究

Raghu, Ganesh; Mouded, Majd; Prasse, Antje; Stebbins, Christopher; Zhao, Guolin; Song, Guochen; Arefayene, Million; Violette, Shelia M; Gallagher, Diana; Gibson, Kevin F

Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells

下一代布鲁顿酪氨酸激酶抑制剂 BIIB091 可选择性地有效抑制 B 细胞和 Fc 受体信号传导以及 B 细胞和髓细胞中的下游功能

Eris Bame, Hao Tang, Jeremy C Burns, Million Arefayene, Klaus Michelsen, Bin Ma, Isaac Marx, Robin Prince, Allie M Roach, Urjana Poreci, Douglas Donaldson, Patrick Cullen, Fergal Casey, Jing Zhu, Thomas M Carlile, Dipen Sangurdekar, Baohong Zhang, Patrick Trapa, Joseph Santoro, Param Muragan, Alex P

Exclusive breastfeeding practice and its associated factors among children aged 6-23 months in Woldia Town, Northwest Ethiopia

埃塞俄比亚西北部沃尔迪亚镇6-23个月龄儿童纯母乳喂养情况及其相关因素

Yimer, Desale Sisay; Adem, Omer Seid; Arefayene, Mastewal; Chanie, Tefera; Endalifer, Melese Linger

MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma

MUC1 促进自发性胰腺腺癌小鼠模型中的肿瘤进展并导致免疫抑制

Teresa L Tinder, Durai B Subramani, Gargi D Basu, Judy M Bradley, Jorge Schettini, Arefayene Million, Todd Skaar, Pinku Mukherjee