日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of Pyrimidoindolones as Novel Family VIII Bromodomain Binders

发现嘧啶并吲哚酮类化合物作为新型VIII族溴结构域结合剂

Boerth, Jeffrey A; Schimpl, Marianne; Lucas, Simon C C; Zhang, Jingwen; Code, Erin L; Embrey, Kevin J; Rawlins, Philip B; Wang, Haixia; Storer, R Ian; Di Fruscia, Paolo; Nelson, Jennifer E; Milbradt, Alexander G; Börjesson, Ulf; Gohlke, Andrea; Korboukh, Victoria; Gopalsamy, Ariamala

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

2,4 二氨基喹唑啉抑制剂对脱帽清除酶 DcpS 的体内外影响:SMN 转录水平的环境特异性调节

Jonathan J Cherry, Christine J DiDonato, Elliot J Androphy, Alessandro Calo, Kyle Potter, Sara K Custer, Sarah Du, Timothy L Foley, Ariamala Gopalsamy, Emily J Reedich, Susana M Gordo, William Gordon, Natalie Hosea, Lyn H Jones, Daniel K Krizay, Gregory LaRosa, Hongxia Li, Sachin Mathur, Carol A Men

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

大环IL-17A拮抗剂的结合位点阐明和结构导向设计

Shenping Liu ,Leslie A Dakin ,Li Xing ,Jane M Withka ,Parag V Sahasrabudhe ,Wei Li ,Mary Ellen Banker ,Paul Balbo ,Suman Shanker ,Boris A Chrunyk ,Zuojun Guo ,Jinshan M Chen ,Jennifer A Young ,Guoyun Bai ,Jeremy T Starr ,Stephen W Wright ,Joerg Bussenius ,Sheng Tan ,Ariamala Gopalsamy ,Bruce A Lefker ,Fabien Vincent ,Lyn H Jones ,Hua Xu ,Lise R Hoth ,Kieran F Geoghegan ,Xiayang Qiu ,Mark E Bunnage ,Atli Thorarensen