日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

L-DOS47 Elevates Pancreatic Cancer Tumor pH and Enhances Response to Immunotherapy

L-DOS47 可提高胰腺癌肿瘤 pH 值并增强对免疫疗法的反应

Bruna Victorasso Jardim-Perassi ,Pietro Irrera ,Oluwaseyi E Oluwatola ,Dominique Abrahams ,Veronica C Estrella ,Bryce Ordway ,Samantha R Byrne ,Andrew A Ojeda ,Christopher J Whelan ,Jongphil Kim ,Matthew S Beatty ,Sultan Damgaci-Erturk ,Dario Livio Longo ,Kim J Gaspar ,Gabrielle M Siegers ,Barbara A Centeno ,Justin Y C Lau ,Shari A Pilon-Thomas ,Arig Ibrahim-Hashim ,Robert J Gillies

Experimental and phylogenetic evidence for correlated gene expression evolution in endometrial and skin fibroblasts

子宫内膜和皮肤成纤维细胞中相关基因表达进化的实验和系统发育证据

Anasuya Dighe, Jamie Maziarz, Arig Ibrahim-Hashim, Robert A Gatenby, Kshitiz, Andre Levchenko, Günter P Wagner

Immunomodulatory and pro-oncologic effects of ketamine and isoflurane anesthetics in a murine model

氯胺酮和异氟烷麻醉剂在小鼠模型中的免疫调节和促肿瘤作用

Dominique Abrahams, Arig Ibrahim-Hashim, Robert S Ackerman, Joel S Brown, Christopher J Whelan, Megan B Garfinkel, Robert A Gatenby, Aaron R Muncey

Artificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race

人工选择宿主对肿瘤生长的抵抗力以及随后的癌细胞适应性:一场进化的军备竞赛

Arig Ibrahim-Hashim, Kimberly Luddy, Dominique Abrahams, Pedro Enriquez-Navas, Sultan Damgaci, Jiqiang Yao, Tingan Chen, Marilyn M Bui, Robert J Gillies, Cliona O'Farrelly, Christina L Richards, Joel S Brown, Robert A Gatenby

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

细胞在淋巴结中产生酸性微环境,以抑制自身的效应功能

Hao Wu #, Veronica Estrella #, Matthew Beatty, Dominique Abrahams, Asmaa El-Kenawi, Shonagh Russell, Arig Ibrahim-Hashim, Dario Livio Longo, Yana K Reshetnyak, Anna Moshnikova, Oleg A Andreev, Kimberly Luddy, Mehdi Damaghi, Krithika Kodumudi, Smitha R Pillai, Pedro Enriquez-Navas, Shari Pilon-Thomas

Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer

酸性通过改变前列腺癌中的巨噬细胞表型来促进肿瘤进展

Asmaa El-Kenawi, Chandler Gatenbee, Mark Robertson-Tessi, Rafael Bravo, Jasreman Dhillon, Yoganand Balagurunathan, Anders Berglund, Naveen Vishvakarma, Arig Ibrahim-Hashim, Jung Choi, Kimberly Luddy, Robert Gatenby, Shari Pilon-Thomas, Alexander Anderson, Brian Ruffell, Robert Gillies

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

酸通过抑制 mTOR 暂停缺氧状态下的昼夜节律

Zandra E Walton, Chirag H Patel, Rebekah C Brooks, Yongjun Yu, Arig Ibrahim-Hashim, Malini Riddle, Alessandra Porcu, Tianying Jiang, Brett L Ecker, Feven Tameire, Constantinos Koumenis, Ashani T Weeraratna, David K Welsh, Robert Gillies, James C Alwine, Lin Zhang, Jonathan D Powell, Chi V Dang

Defining Cancer Subpopulations by Adaptive Strategies Rather Than Molecular Properties Provides Novel Insights into Intratumoral Evolution

通过自适应策略而非分子特性来定义癌症亚群,为肿瘤内进化提供了新的见解

Arig Ibrahim-Hashim, Mark Robertson-Tessi, Pedro M Enriquez-Navas, Mehdi Damaghi, Yoganand Balagurunathan, Jonathan W Wojtkowiak, Shonagh Russell, Kam Yoonseok, Mark C Lloyd, Marilyn M Bui, Joel S Brown, Alexander R A Anderson, Robert J Gillies, Robert A Gatenby

Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation

癌症相关间充质基质通过 NF-κB 激活促进骨肉瘤细胞对肿瘤内酸中毒的干细胞性

Sofia Avnet, Gemma Di Pompo, Tokuhiro Chano, Costantino Errani, Arig Ibrahim-Hashim, Robert J Gillies, Davide Maria Donati, Nicola Baldini

Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance

间歇性缺氧选择增加生存、侵袭和治疗抵抗力的基因型和表型

Daniel Verduzco, Mark Lloyd, Liping Xu, Arig Ibrahim-Hashim, Yoganand Balagurunathan, Robert A Gatenby, Robert J Gillies