日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms and regulation of substrate degradation by the 26S proteasome

26S蛋白酶体底物降解的机制和调控

Arkinson, Connor; Dong, Ken C; Gee, Christine L; Martin, Andreas

Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1

降解的 26S 蛋白酶体的结构图谱揭示了 TXNL1 的构象特异性结合

Arkinson, Connor; Gee, Christine L; Zhang, Zeyuan; Dong, Ken C; Martin, Andreas

NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome.

NUB1 捕获未折叠的 FAT10,使其通过 26S 蛋白酶体进行不依赖泛素的降解

Arkinson Connor, Dong Ken C, Gee Christine L, Costello Shawn M, Soe Aimee Chi, Hura Greg L, Marqusee Susan, Martin Andreas

Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement

Faf1通过促进泛素结合来加速p97介导的蛋白质展开。

Liao, Zengwei; Arkinson, Connor; Martin, Andreas

Nub1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome

Nub1 捕获未折叠的 FAT10,通过 26S 蛋白酶体进行不依赖泛素的降解

Connor Arkinson, Ken C Dong, Christine L Gee, Shawn M Costello, Susan Marqusee, Andreas Martin

The Ufd1 cofactor determines the linkage specificity of polyubiquitin chain engagement by the AAA+ ATPase Cdc48

Ufd1 辅因子决定了 AAA+ ATPase Cdc48 与多聚泛素链结合的连接特异性

Williams, Cameron; Dong, Ken C; Arkinson, Connor; Martin, Andreas

Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1

使用 UBIMAX 分析泛素信号传导,揭示了 DNA 损伤和 SCFβ-Trcp1 依赖的肌动蛋白组织蛋白 Dbn1 泛素化

Camilla S Colding-Christensen #, Ellen S Kakulidis #, Javier Arroyo-Gomez, Ivo A Hendriks, Connor Arkinson, Zita Fábián, Agnieszka Gambus, Niels Mailand, Julien P Duxin, Michael L Nielsen

Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination

FANCI-FANCD2泛素化相互依赖的结构和生化基础

Lemonidis, Kimon; Rennie, Martin L; Arkinson, Connor; Chaugule, Viduth K; Clarke, Mairi; Streetley, James; Walden, Helen

Preparation of site-specifically fluorophore-labeled polyubiquitin chains for FRET studies of Cdc48 substrate processing

制备位点特异性荧光标记的多泛素链,用于 Cdc48 底物加工的 FRET 研究

Cameron Williams, Ken C Dong, Connor Arkinson, Andreas Martin

Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site

Cryo-EM 揭示了通过隐秘结合位点抑制 USP1 的机制

Martin L Rennie, Connor Arkinson, Viduth K Chaugule, Helen Walden