日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanisms and regulation of substrate degradation by the 26S proteasome

26S蛋白酶体底物降解的机制和调控

Arkinson, Connor; Dong, Ken C; Gee, Christine L; Martin, Andreas

Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1

降解的 26S 蛋白酶体的结构图谱揭示了 TXNL1 的构象特异性结合

Arkinson, Connor; Gee, Christine L; Zhang, Zeyuan; Dong, Ken C; Martin, Andreas

NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome.

NUB1 捕获未折叠的 FAT10,使其通过 26S 蛋白酶体进行不依赖泛素的降解

Arkinson Connor, Dong Ken C, Gee Christine L, Costello Shawn M, Soe Aimee Chi, Hura Greg L, Marqusee Susan, Martin Andreas

Faf1 accelerates p97-mediated protein unfolding by promoting ubiquitin engagement

Faf1通过促进泛素结合来加速p97介导的蛋白质展开。

Liao, Zengwei; Arkinson, Connor; Martin, Andreas

The Ufd1 cofactor determines the linkage specificity of polyubiquitin chain engagement by the AAA+ ATPase Cdc48

Ufd1 辅因子决定了 AAA+ ATPase Cdc48 与多聚泛素链结合的连接特异性

Williams, Cameron; Dong, Ken C; Arkinson, Connor; Martin, Andreas

Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination

FANCI-FANCD2泛素化相互依赖的结构和生化基础

Lemonidis, Kimon; Rennie, Martin L; Arkinson, Connor; Chaugule, Viduth K; Clarke, Mairi; Streetley, James; Walden, Helen

Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening

通过片段筛选对范可尼贫血泛素结合酶Ube2T进行变构靶向

Morreale, Francesca E; Bortoluzzi, Alessio; Chaugule, Viduth K; Arkinson, Connor; Walden, Helen; Ciulli, Alessio