日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Schizophrenia risk variants modulate transcription factor binding and gene expression in cortical cell types

精神分裂症风险变异体调节皮质细胞类型中的转录因子结合和基因表达

Gerstner, Nathalie; Fröhlich, Anna S; Matosin, Natalie; Binder, Elisabeth B; Knauer-Arloth, Janine

FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice

谷氨酸能前脑神经元中的FKBP51促进雌性小鼠早期生活应激的接种

van Doeselaar, Lotte; Abromeit, Alexandra; Stark, Tibor; Menegaz, Danusa; Ballmann, Markus; Mitra, Shiladitya; Yang, Huanqing; Rehawi, Ghalia; Huettl, Rosa-Eva; Bordes, Joeri; Narayan, Sowmya; Harbich, Daniela; Deussing, Jan M; Rammes, Gerhard; Czisch, Michael; Knauer-Arloth, Janine; Eder, Matthias; Lopez, Juan Pablo; Schmidt, Mathias V

Contrasting genetic predisposition and diagnosis in psychiatric disorders: A multi-omic single-nucleus analysis of the human OFC

精神疾病中遗传易感性和诊断的对比:人类眶额皮层多组学单核分析

Gerstner, Nathalie; Fröhlich, Anna S; Matosin, Natalie; Gagliardi, Miriam; Cruceanu, Cristiana; Ködel, Maik; Rex-Haffner, Monika; Tu, Xinming; Mostafavi, Sara; Ziller, Michael J; Binder, Elisabeth B; Knauer-Arloth, Janine

Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons

外显子变异相互作用和多模态证据表明,严重精神疾病中存在影响兴奋性神经元的内分泌失调。

Worf, Karolina; Matosin, Natalie; Gerstner, Nathalie; Fröhlich, Anna S; Koller, Anna C; Degenhardt, Franziska; Thiele, Holger; Rietschel, Marcella; Udawela, Madhara; Scarr, Elizabeth; Dean, Brian; Theis, Fabian J; Mueller, Nikola S; Knauer-Arloth, Janine

Integrative gene and isoform co-expression networks reveal regulatory rewiring in stress-related psychiatric disorders

整合基因和亚型共表达网络揭示了应激相关精神疾病中的调控重连

Rehawi, Ghalia; Hagenberg, Jonas; Sämann, Philipp G; Moyon, Lambert; Binder, Elisabeth; List, Markus; Marsico, Annalisa; Knauer-Arloth, Janine

345. CHARACTERISING THE NEUROPEPTIDE LANDSCAPE OF THE POSTMORTEM HUMAN ORBITOFRONTAL CORTEX IN HEALTH, FOLLOWING SEVERE CHILDHOOD ADVERSITY AND IN PSYCHOPATHOLOGY

345. 描述健康人、经历严重童年逆境者以及精神病理患者死后人眶额皮质的神经肽图谱

Padua, David; Vu, John P; Germano, Patrizia M; Pisegna, Joseph R; Edmond, K Z; Kaul, D; Curry, A R; Ahsan, T; Gerstner, N; Fröhlich, A S; Knauer-Arloth, J; Binder, E B; Verhaert, P; Ooi, L; Ellis, S R; Matosin, N

Astrocytic glutamate regulation is shaped by adversity and glucocorticoid signalling

星形胶质细胞谷氨酸调节受逆境和糖皮质激素信号的影响

Kaul, Dominic; Curry, Amber R; Gerstner, Nathalie; Fröhlich, Anna S; Krontira, Anthi C; Kyrousi, Christina; Smith, Caine C; Sutherland, Greg T; Dottori, Mirella; Ziller, Michael J; Chatzinakos, Christos; Daskalakis, Nikolaos P; Cappello, Silvia; Czamara, Darina; Binder, Elisabeth B; Cruceanu, Cristiana; Knauer-Arloth, Janine; Mechawar, Naguib; Schwab, Sibylle G; Ooi, Lezanne; Matosin, Natalie

Single-nucleus transcriptomic profiling of human orbitofrontal cortex reveals convergent effects of aging and psychiatric disease

人类眶额皮质的单核转录组分析揭示了衰老和精神疾病的聚合效应

Anna S Fröhlich, Nathalie Gerstner, Miriam Gagliardi, Maik Ködel, Natan Yusupov, Natalie Matosin, Darina Czamara, Susann Sauer, Simone Roeh, Vanessa Murek, Chris Chatzinakos, Nikolaos P Daskalakis, Janine Knauer-Arloth, Michael J Ziller, Elisabeth B Binder

Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies

FKBP51 亚型的差异动力学和作用及其对靶向治疗的影响

Silvia Martinelli, Kathrin Hafner, Maik Koedel, Janine Knauer-Arloth, Nils C Gassen, Elisabeth B Binder

longmixr: a tool for robust clustering of high-dimensional cross-sectional and longitudinal variables of mixed data types

longmixr:一种用于对混合数据类型的高维横截面和纵向变量进行稳健聚类的工具

Hagenberg, Jonas; Budde, Monika; Pandeva, Teodora; Kondofersky, Ivan; Schaupp, Sabrina K; Theis, Fabian J; Schulze, Thomas G; Müller, Nikola S; Heilbronner, Urs; Batra, Richa; Knauer-Arloth, Janine