日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia

调控GATA1表达作为治疗Diamond-Blackfan贫血症的通用基因疗法

Richard A Voit ,Xiaotian Liao ,Alexis Caulier ,Mateusz Antoszewski ,Blake Cohen ,Myriam Armant ,Henry Y Lu ,Travis J Fleming ,Elena Kamal ,Lara Wahlster ,Aoife M Roche ,John K Everett ,Angelina Petrichenko ,Mei-Mei Huang ,William Clarke ,Kasiani C Myers ,Craig Forester ,Antonio Perez-Atayde ,Frederic D Bushman ,Danilo Pellin ,Akiko Shimamura ,David A Williams ,Vijay G Sankaran

Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia

调控GATA1表达作为治疗Diamond-Blackfan贫血症的通用基因疗法

Richard A Voit,Xiaotian Liao,Alexis Caulier,Mateusz Antoszewski,Blake Cohen,Myriam Armant,Henry Y Lu,Travis J Fleming,Elena Kamal,Lara Wahlster,Aoife M Roche,John K Everett,Angelina Petrichenko,Mei-Mei Huang,William Clarke,Kasiani C Myers,Craig Forester,Antonio Perez-Atayde,Frederic D Bushman,Danilo Pellin,Akiko Shimamura,David A Williams,Vijay G Sankaran

Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells

无需体外培养的基因编辑可避免对人类造血干细胞造成基因毒性。

Jing Zeng,My Anh Nguyen,Pengpeng Liu,Lucas Ferreira da Silva,Sébastien Levesque,Linda Y Lin,David G Justus,Karl Petri,Kendell Clement,Shaina N Porter,Archana Verma,Nola R Neri,Tolulope Rosanwo,Marioara-Felicia Ciuculescu,Daniela Abriss,Esther Mintzer,Stacy A Maitland,Selami Demirci,Hye Ji Cha,Stuart H Orkin,John F Tisdale,David A Williams,Lihua Julie Zhu,Shondra M Pruett-Miller,Luca Pinello,J Keith Joung,Vikram Pattanayak,John P Manis,Myriam Armant,Danilo Pellin,Christian Brendel,Scot A Wolfe,Daniel E Bauer  0

Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells

无需体外培养的基因编辑可避免对人类造血干细胞造成基因毒性。

Jing Zeng ,My Anh Nguyen ,Pengpeng Liu ,Lucas Ferreira da Silva ,Sébastien Levesque ,Linda Y Lin ,David G Justus ,Karl Petri ,Kendell Clement ,Shaina N Porter ,Archana Verma ,Nola R Neri ,Tolulope Rosanwo ,Marioara-Felicia Ciuculescu ,Daniela Abriss ,Esther Mintzer ,Stacy A Maitland ,Selami Demirci ,Hye Ji Cha ,Stuart H Orkin ,John F Tisdale ,David A Williams ,Lihua Julie Zhu ,Shondra M Pruett-Miller ,Luca Pinello ,J Keith Joung ,Vikram Pattanayak ,John P Manis ,Myriam Armant ,Danilo Pellin ,Christian Brendel ,Scot A Wolfe ,Daniel E Bauer

Cultivated autologous limbal epithelial cell (CALEC) transplantation for limbal tem cell deficiency: a phase I/II clinical trial of the first xenobiotic-free, serum-free, antibiotic-free manufacturing protocol developed in the US

用于治疗角膜缘上皮细胞缺乏症的自体培养角膜缘上皮细胞(CALEC)移植:一项在美国开发的首个无异种物质、无血清、无抗生素生产方案的I/II期临床试验

Jurkunas, Ula V; Kaufman, Aaron R; Yin, Jia; Ayala, Allison; Maguire, Maureen; Samarakoon, Lassana; Johns, Lynette K; Parekh, Mohit; Li, Sanming; Gauthier, Alex; Negre, Helene; Shaw, Kit L; Hernandez Rodriguez, Diego E; Daley, Heather; Dana, Reza; Armant, Myriam; Ritz, Jerome

Short internal open reading frames repress the translation of N-terminally truncated proteoforms

短的内部开放阅读框抑制N端截短的蛋白质形式的翻译

Raphael Fettig # ,Zita Gonda # ,Niklas Walter # ,Paul Sallmann ,Christiane Thanisch ,Markus Winter ,Susanne Bauer ,Lei Zhang ,Greta Linden ,Margarethe Litfin ,Marina Khamanaeva ,Sarah Storm ,Christina Münzing ,Christelle Etard ,Olivier Armant ,Olalla Vázquez ,Olivier Kassel

Human placentation: foundations and implications for reproductive endocrinology and infertility

人类胎盘形成:基础及其对生殖内分泌学和不孕症的影响

Prabaharan, Elakkiya; Armant, D Randall; Drewlo, Sascha

AOP-helpFinder 3.0: from text mining to network visualization of key event relationships, and knowledge integration from multiple sources

AOP-helpFinder 3.0:从文本挖掘到关键事件关系的网络可视化,以及来自多个来源的知识整合

Jaylet, Thomas; Jornod, Florence; Capdet, Quentin; Armant, Olivier; Audouze, Karine

Host defense alteration in Caenorhabditis elegans after evolution under ionizing radiation

秀丽隐杆线虫在电离辐射进化后宿主防御机制的改变

Quevarec, Loïc; Morran, Levi T; Dufourcq-Sekatcheff, Elizabeth; Armant, Olivier; Adam-Guillermin, Christelle; Bonzom, Jean-Marc; Réale, Denis

Clonal selection of hematopoietic stem cells after gene therapy for sickle cell disease

镰状细胞病基因治疗后造血干细胞的克隆选择

Michael Spencer Chapman # ,Alyssa H Cull #,Marioara F Ciuculescu,Erica B Esrick ,Emily Mitchell ,Hyunchul Jung,Laura O'Neill,Kirsty Roberts,Margarete A Fabre ,Nicholas Williams,Jyoti Nangalia ,Joanne Quinton,James M Fox,Danilo Pellin,Julie Makani ,Myriam Armant,David A Williams ,Peter J Campbell,David G Kent