Sym024 Interacts with a Unique Epitope on the CD73 Homodimer, Favoring Effective Bivalent Binding to Improve Anti-PD-1 Therapy.
Sym024 与 CD73 同源二聚体上的独特表位相互作用,有利于有效的二价结合,从而改善抗 PD-1 疗法。
期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-2406
Jakobsen Janus S, Grandal Michael M, Hansen Randi W, Bansia Harsh, Armbruster Emily, Theret Isabelle, Skartved Niels Jørgen Ã, Hald Rikke, Melander Maria C, Worsaae Anne, Riva Matteo, Reckzeh Kristian, Vuillard Laurent, Lantto Johan, des Georges Amedee, Fröhlich Camilla