Dysregulation of human ClpP using small molecules with piperazine-based scaffold for diffuse intrinsic pontine glioma therapy validated by patient-derived tumor organoids
利用哌嗪骨架小分子调控人ClpP失调治疗弥漫性内生性脑桥胶质瘤，并通过患者来源的肿瘤类器官验证其疗效
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doi:10.21203/rs.3.rs-8230151/v1
Miciaccia, Morena; Armenise, Domenico; Baldelli, Olga Maria; Liturri, Anselma; Mammone, Mariachiara; Graziano, Giovanni; Contino, Marialessandra; Rizzo, Francesca; Polosa, Paola Loguercio; Bruni, Francesco; Deligne, Clémence; Broutier, Laura; Cavallaro, Gianfranco; Fortuna, Cosimo Gianluca; Tolomeo, Anna; Green, Cadell; Bonifazi, Alessandro; Majaesic, Emily; Barghash, Marim M; Lee, Nok Pang Josh; Houry, Walid A; Gratteri, Carmen; Talarico, Carmine; Filieri, Silvana; Micalizzi, Giuseppe; Donnarumma, Danilo; Dugo, Paola; Mondello, Luigi; Sardanelli, Anna Maria; Nazarian, Javad; Ferorelli, Savina; Perrone, Maria Grazia; Scilimati, Antonio
