日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8(+) T cells in lymph nodes

Flt3L介导的肿瘤cDC1扩增通过启动淋巴结中的干细胞样CD8(+) T细胞来增强免疫疗法。

Lai, Junyun; Chan, Cheok Weng; Armitage, Jesse D; Audsley, Katherine M; Huang, Yu-Kuan; Derrick, Emily B; Carstensen, Laura S; Scheffler, Christina M; Jones, Matt E; Sek, Kevin; Principe, Nicola; Kim, Joelle S; House, Imran G; Chen, Amanda X Y; Yap, Kah Min; Middelburg, Jim; Munoz, Isabelle; Nguyen, Dat; Tong, Junming; Hoang, Thang X; Todd, Kirsten L; Evrard, Maximilien; Chee, Jonathan; Mackay, Laura K; Forrest, Alistair R R; Parish, Ian A; Bosco, Anthony; Waithman, Jason; Beavis, Paul A; Darcy, Phillip K

Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery

通过重编程CAR T细胞中的内源基因,实现肿瘤特异性有效载荷递送。

Chen, Amanda X Y; Yap, Kah Min; Kim, Joelle S; Sek, Kevin; Huang, Yu-Kuan; Dunbar, Phoebe A; Wiebking, Volker; Armitage, Jesse D; Munoz, Isabelle; Todd, Kirsten L; Derrick, Emily B; Nguyen, Dat; Tong, Junming; Chan, Cheok Weng; Hoang, Thang X; Audsley, Katherine M; van Elsas, Marit J; Middelburg, Jim; Lee, Joel N; de Menezes, Maria N; Cole, Thomas J; Li, Jasmine; Scheffler, Christina; Scott, Andrew M; Mackay, Laura K; Waithman, Jason; Oliaro, Jane; Harrison, Simon J; Parish, Ian A; Lai, Junyun; Porteus, Matthew H; House, Imran G; Darcy, Phillip K; Beavis, Paul A

Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors.

肿瘤部位定向的 A1R 表达可增强 CAR T 细胞功能,提高对实体瘤的疗效

Sek Kevin, Chen Amanda X Y, Cole Thomas, Armitage Jesse D, Tong Junming, Yap Kah Min, Munoz Isabelle, Dunbar Phoebe A, Wu Shiyi, van Elsas Marit J, Hidajat Olivia, Scheffler Christina, Giuffrida Lauren, Henderson Melissa A, Meyran Deborah, Souza-Fonseca-Guimaraes Fernando, Nguyen Dat, Huang Yu-Kuan, de Menezes Maria N, Derrick Emily B, Chan Cheok Weng, Todd Kirsten L, Chan Jack D, Li Jasmine, Lai Junyun, Petley Emma V, Mardiana Sherly, Bosco Anthony, Waithman Jason, Parish Ian A, Mølck Christina, Stewart Gregory D, Kats Lev, House Imran G, Darcy Phillip K, Beavis Paul A

Interleukin-4 modulates type I interferon to augment antitumor immunity.

白细胞介素-4调节I型干扰素,从而增强抗肿瘤免疫力

Newnes Hannah V, Armitage Jesse D, Buzzai Anthony C, de Jong Emma, Audsley Katherine M, Barnes Samantha A, Srinivasan Shamini, Serralha Michael, Fear Vanessa S, Guo Belinda B, Jones Matt E, Forrest Alistair R R, Foley Bree, Darcy Phil K, Beavis Paul A, Bosco Anthony, Waithman Jason

Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia

DYRK1A抑制剂在唐氏综合征急性淋巴细胞白血病新型模型中的疗效

Carey-Smith, Shannon L; Simad, Maryam H; Panchal, Kunjal; Aya-Bonilla, Carlos; Smolders, Hannah; Lin, Sang; Armitage, Jesse D; Nguyen, Vivien T; Bentley, Kathryn; Ford, Jette; Singh, Sajla; Oommen, Joyce; Laurent, Anouchka P; Mercher, Thomas; Crispino, John D; Montgomery, Andrew P; Kassiou, Michael; Besson, Thierry; Deau, Emmanuel; Meijer, Laurent; Cheung, Laurence C; Kotecha, Rishi S; Malinge, Sébastien

Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years

单细胞转录组学揭示了出生至5岁期间发育调控的脂多糖反应的细胞类型特异性特征

Read, James F; Serralha, Michael; Armitage, Jesse D; Iqbal, Muhammad Munir; Cruickshank, Mark N; Saxena, Alka; Strickland, Deborah H; Waithman, Jason; Holt, Patrick G; Bosco, Anthony

Tissue-resident memory T cells in the era of (Neo) adjuvant melanoma management

组织驻留记忆T细胞在(新)辅助黑色素瘤治疗时代的作用

Plunkett, Kai R; Armitage, Jesse D; Inderjeeth, Andrisha-Jade; McDonnell, Alison M; Waithman, Jason; Lau, Peter K H

Transcriptional profiling of circulating mononuclear cells from patients with chronic obstructive pulmonary disease receiving mesenchymal stromal cell infusions

接受间充质干细胞输注的慢性阻塞性肺病患者循环单核细胞的转录组分析

Armitage, Jesse D; Tan, Dino B A; Sturm, Marian; Moodley, Yuben P

Directing the Future Breakthroughs in Immunotherapy: The Importance of a Holistic Approach to the Tumour Microenvironment

引领免疫疗法的未来突破:肿瘤微环境整体方法的重要性

Newnes, Hannah V; Armitage, Jesse D; Audsley, Katherine M; Bosco, Anthony; Waithman, Jason