日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct Clinical Phenotypes in KIF1A-Associated Neurological Disorders Result from Different Amino Acid Substitutions at the Same Residue in KIF1A

KIF1A相关神经系统疾病的不同临床表型是由KIF1A蛋白同一残基上不同的氨基酸替换造成的。

Lu Rao ,Wenxing Li ,Yufeng Shen ,Wendy K Chung ,Arne Gennerich

Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L

冷冻电镜揭示了驱动蛋白KIF1A的持续运动机制及其致病性变体P305L的影响

Matthieu P M H Benoit # ,Lu Rao # ,Ana B Asenjo ,Arne Gennerich ,Hernando Sosa

Kinesin-14 HSET and KlpA are non-processive microtubule motors with load-dependent power strokes

驱动蛋白-14 HSET 和 KlpA 是非连续性微管马达,其动力冲程取决于负载。

Xinglei Liu # ,Lu Rao # ,Weihong Qiu ,Florian Berger ,Arne Gennerich

Insect Cell-Based Expression of Cytoskeletal Motor Proteins for Single-Molecule Studies

基于昆虫细胞的细胞骨架运动蛋白表达及其单分子研究

Xinglei Liu, Arne Gennerich

Measurements of the Force-Dependent Detachment Rates of Cytoplasmic Dynein from Microtubules

细胞质动力蛋白与微管力依赖性分离率的测量

Xinglei Liu, Lu Rao, Arne Gennerich

ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain-of-function

与肌萎缩侧索硬化症 (ALS) 相关的 KIF5A ΔExon27 突变体通过功能获得性突变导致神经元毒性。

Devesh C Pant # ,Janani Parameswaran # ,Lu Rao ,Isabel Loss ,Ganesh Chilukuri ,Rosanna Parlato ,Liang Shi ,Jonathan D Glass ,Gary J Bassell ,Philipp Koch ,Rüstem Yilmaz ,Jochen H Weishaupt ,Arne Gennerich ,Jie Jiang

Doublecortin and JIP3 are neural-specific counteracting regulators of dynein-mediated retrograde trafficking

双皮质素和JIP3是神经特异性拮抗动力蛋白介导的逆行运输的调节因子。

Xiaoqin Fu ,Lu Rao ,Peijun Li ,Xinglei Liu ,Qi Wang ,Alexander I Son ,Arne Gennerich ,Judy Shih-Hwa Liu

Single-Molecule Studies on the Motion and Force Generation of the Kinesin-3 Motor KIF1A

关于 Kinesin-3 马达 KIF1A 的运动和力产生的单分子研究

Lu Rao, Arne Gennerich

A highly conserved 310 helix within the kinesin motor domain is critical for kinesin function and human health

驱动蛋白运动域内高度保守的 310 螺旋对于驱动蛋白的功能和人类健康至关重要

Aileen J Lam, Lu Rao, Yuzu Anazawa, Kyoko Okada, Kyoko Chiba, Mariah Dacy, Shinsuke Niwa, Arne Gennerich, Dan W Nowakowski, Richard J McKenney

Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms

驱动蛋白-3马达KIF1A的致病突变通过变构机制减弱动力产生和运动。

Breane G Budaitis # ,Shashank Jariwala # ,Lu Rao # ,Yang Yue ,David Sept ,Kristen J Verhey ,Arne Gennerich