AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study
人工智能/机器学习结合新一代测序技术对VHH免疫库进行测序,能够快速鉴定新生的人源化和序列优化的单域抗体:一项前瞻性案例研究
期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2023.1249247
Arras, Paul; Yoo, Han Byul; Pekar, Lukas; Clarke, Thomas; Friedrich, Lukas; Schröter, Christian; Schanz, Jennifer; Tonillo, Jason; Siegmund, Vanessa; Doerner, Achim; Krah, Simon; Guarnera, Enrico; Zielonka, Stefan; Evers, Andreas