日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting the ERα DBD-LBD Interface with Mitoxantrone Disrupts Receptor Function through Proteasomal Degradation.

利用米托蒽醌靶向 ERα DBD-LBD 界面,通过蛋白酶体降解破坏受体功能。

Wang Han, Luo Yuxuan, Artham Sandeep, Wang Qianqian, Peng Yi, Yun Zixi, Li Xinyue, Wu Chen, Liu Zhenghao, Weber-Bonk Kristen L, Pai Chun-Peng, Cao Yuan, Yue Jiangan, Park Sunghee, Keri Ruth A, Geng Lisheng, McDonnell Donald P, Kao Hung-Ying, Yang Sichun

Dietary methionine restriction primes T cell metabolism for activation and tumor inhibition and enhances the efficacy of immune checkpoint blockade

限制膳食蛋氨酸摄入可促进T细胞代谢,使其活化并抑制肿瘤,同时增强免疫检查点阻断疗法的疗效。

Qing, Xiaoqing; Chakraborty, Binita; Liu, Panpan; Artham, Sandeep; Juras, Patrick K; Guan, Dongyin; Pauken, Kristen E; Chang, Ching-Yi; Gao, Xia

Eosinophilia in cancer and its regulation by sex hormones

癌症中的嗜酸性粒细胞增多症及其受性激素的调节

Artham, Sandeep; Chang, Ching-Yi; McDonnell, Donald P

Inhibition of estrogen signaling in myeloid cells increases tumor immunity in melanoma

抑制髓系细胞中的雌激素信号传导可增强黑色素瘤的肿瘤免疫力

Chakraborty, Binita; Byemerwa, Jovita; Shepherd, Jonathan; Haines, Corinne N; Baldi, Robert; Gong, Weida; Liu, Wen; Mukherjee, Debarati; Artham, Sandeep; Lim, Felicia; Bae, Yeeun; Brueckner, Olivia; Tavares, Kendall; Wardell, Suzanne E; Hanks, Brent A; Perou, Charles M; Chang, Ching-Yi; McDonnell, Donald P

The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor.

临床相关 ESR1 突变体的药理学失调可通过配体激活的野生型受体恢复正常

Andreano Kaitlyn J, Baker Jennifer G, Park Sunghee, Safi Rachid, Artham Sandeep, Oesterreich Steffi, Jeselsohn Rinath, Brown Myles, Sammons Sarah, Wardell Suzanne E, Chang Ching-Yi, Norris John D, McDonnell Donald P

Modulation in the microRNA repertoire is responsible for the stage-specific effects of Akt suppression on murine neuroendocrine prostate cancer.

微RNA库的调节是Akt抑制对小鼠神经内分泌前列腺癌产生阶段特异性效应的原因

Alwhaibi Abdulrahman, Gao Fei, Artham Sandeep, Hsia Bernard M, Mondal Ashis, Kolhe Ravindra, Somanath Payaningal R

Modulation of long-term endothelial-barrier integrity is conditional to the cross-talk between Akt and Src signaling

长期内皮屏障完整性的调节取决于Akt和Src信号通路之间的相互作用。

Gao, Fei; Sabbineni, Harika; Artham, Sandeep; Somanath, Payaningal R

TNFα induces inflammatory stress response in microvascular endothelial cells via Akt- and P38 MAP kinase-mediated thrombospondin-1 expression

TNFα通过Akt和P38 MAP激酶介导的血小板反应蛋白-1表达诱导微血管内皮细胞的炎症应激反应。

Fairaq, Arwa; Goc, Anna; Artham, Sandeep; Sabbineni, Harika; Somanath, Payaningal R