日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEM

二硫键约束的Fab片段克服了高分辨率单颗粒冷冻电镜成像的目标尺寸限制。

Kung, Jennifer E; Johnson, Matthew C; Tegunov, Dimitry; Jao, Christine C; Wu, Ping; Oh, Angela; Lin, May; Daria, Jose M; Koth, Christopher M; Arthur, Christopher P; Rohou, Alexis; Sudhamsu, Jawahar

Cryo-EM reveals an unprecedented binding site for Na(V)1.7 inhibitors enabling rational design of potent hybrid inhibitors

冷冻电镜揭示了Na(V)1.7抑制剂前所未有的结合位点,从而能够合理设计高效的混合抑制剂。

Kschonsak, Marc; Jao, Christine C; Arthur, Christopher P; Rohou, Alexis L; Bergeron, Philippe; Ortwine, Daniel F; McKerrall, Steven J; Hackos, David H; Deng, Lunbin; Chen, Jun; Li, Tianbo; Dragovich, Peter S; Volgraf, Matthew; Wright, Matthew R; Payandeh, Jian; Ciferri, Claudio; Tellis, John C

Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 à Resolution.

酵母着丝粒核小体的冷冻电镜结构,分辨率为 2.7 Å

Migl David, Kschonsak Marc, Arthur Christopher P, Khin Yadana, Harrison Stephen C, Ciferri Claudio, Dimitrova Yoana N

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation.

CARD9 的自抑制和聚合形式的结构揭示了 CARD9 和 CARD11 激活的机制

Holliday Michael J, Witt Axel, Rodríguez Gama Alejandro, Walters Benjamin T, Arthur Christopher P, Halfmann Randal, Rohou Alexis, Dueber Erin C, Fairbrother Wayne J

Architecture of the Synaptophysin/Synaptobrevin Complex: Structural Evidence for an Entropic Clustering Function at the Synapse

突触素/突触小泡蛋白复合物的结构:突触处熵聚集功能的结构证据

Adams, Daniel J; Arthur, Christopher P; Stowell, Michael H B

Structure of synaptophysin: a hexameric MARVEL-domain channel protein

突触素的结构:一种六聚体MARVEL结构域通道蛋白

Arthur, Christopher P; Stowell, Michael H B