日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lentiviral gene therapy with reduced-intensity conditioning for sickle cell disease: a phase 1/2 trial

采用减低强度预处理的慢病毒基因疗法治疗镰状细胞病：一项 1/2 期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-025-03662-2
Grimley, Michael; Davies, Stella M; Shrestha, Archana; Shova, Amy; Asnani, Monika; Kent, Michael; Sayani, Farzana; Quinn, Charles T; Niss, Omar; Lutzko, Carolyn; Mehta, Parinda A; Khandelwal, Pooja; Little, Courtney; Chandra, Sharat; Felker, Sydney; Chi, Mengna; Kalfa, Theodosia A; Knight-Madden, Jennifer; Arumugam, Paritha I; Ramos, Kristie N; Witting, Scott; Latham, Teresa; Bushman, Frederic D; Malik, Punam
微生物学
细胞生物学
发表日期：2025
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HGG-07. INVESTIGATING THE ROLE OF SENESCENCE IN PEDIATRIC HIGH-GRADE GLIOMAS

HGG-07. 研究衰老在儿童高级别胶质瘤中的作用

期刊:Molecular Therapy
影响因子:12
doi:10.1038/mt.2009.183
Arumugam, Paritha I; Higashimoto, Tomoyasu; Urbinati, Fabrizia; Modlich, Ute; Nestheide, Shawna; Xia, Ping; Fox, Catherine; Corsinotti, Andrea; Baum, Christopher; Malik, Punam; Chang, Timothy H; Nassar, Alexander; Kleinman, Claudia; Bandopadhayay, Pratiti
胶质瘤
衰老
发表日期：2024
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Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation

GM-CSF在调节代谢和线粒体功能中的作用，对巨噬细胞增殖至关重要

期刊:Mitochondrion
影响因子:4.5
doi:10.1016/j.mito.2021.10.009
Wessendarp, Matthew; Watanabe-Chailland, Miki; Liu, Serena; Stankiewicz, Traci; Ma, Yan; Kasam, Rajesh K; Shima, Kenjiro; Chalk, Claudia; Carey, Brenna; Rosendale, Lindsey-Romick; Dominique Filippi, Marie; Arumugam, Paritha
M-CSF
免疫/内分泌
巨噬细胞
GM-CSF
代谢
线粒体
细胞生物学
巨噬细胞
发表日期：2022
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A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption

由纯合Csf2ra基因敲除引起的遗传性肺泡蛋白沉积症小鼠模型

期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology
影响因子:3.5
doi:10.1152/ajplung.00175.2021
Shima, Kenjiro; Arumugam, Paritha; Sallese, Anthony; Horio, Yuko; Ma, Yan; Trapnell, Cole; Wessendarp, Matthew; Chalk, Claudia; McCarthy, Cormac; Carey, Brenna C; Trapnell, Bruce C; Suzuki, Takuji
发表日期：2022
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Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia.

中性粒细胞胞外陷阱激活人支气管上皮细胞中IL-8和IL-1的表达

期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology
影响因子:3.5
doi:10.1152/ajplung.00144.2019
Hudock Kristin M, Collins Margaret S, Imbrogno Michelle, Snowball John, Kramer Elizabeth L, Brewington John J, Gollomp Kandace, McCarthy Cormac, Ostmann Alicia J, Kopras Elizabeth J, Davidson Cynthia R, Srdiharan Anusha, Arumugam Paritha, Sengupta Shaon, Xu Yan, Worthen G Scott, Trapnell Bruce C, Clancy John Paul
细胞生物学
Human
中性粒细胞
发表日期：2020
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Elimination of the fibrinogen integrin α(M)β(2)-binding motif improves renal pathology in mice with sickle cell anemia

消除纤维蛋白原整合素α(M)β(2)结合基序可改善镰状细胞贫血小鼠的肾脏病理

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2019032342
Nasimuzzaman, Md; Arumugam, Paritha I; Mullins, Eric S; James, Jeanne M; VandenHeuvel, Katherine; Narciso, Marilou G; Shaw, Maureen A; McGraw, Sarah; Aronow, Bruce J; Malik, Punam
细胞生物学
贫血
代谢
发表日期：2019
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Targeting cholesterol homeostasis in lung diseases

针对肺部疾病中的胆固醇稳态进行治疗

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-10879-w
Sallese, Anthony; Suzuki, Takuji; McCarthy, Cormac; Bridges, James; Filuta, Alyssa; Arumugam, Paritha; Shima, Kenjiro; Ma, Yan; Wessendarp, Matthew; Black, Diane; Chalk, Claudia; Carey, Brenna; Trapnell, Bruce C
代谢
发表日期：2017
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Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13

胎盘生长因子通过白三烯和IL-13增强气道高反应性

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI77250
Eiymo Mwa Mpollo, Marthe-Sandrine; Brandt, Eric B; Shanmukhappa, Shiva Kumar; Arumugam, Paritha I; Tiwari, Swati; Loberg, Anastacia; Pillis, Devin; Rizvi, Tilat; Lindsey, Mark; Jonck, Bart; Carmeliet, Peter; Kalra, Vijay K; Le Cras, Timothy D; Ratner, Nancy; Wills-Karp, Marsha; Hershey, Gurjit K Khurana; Malik, Punam
IL-13
发表日期：2016
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Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.

基因手段降低循环凝血酶原水平可改善镰状细胞病小鼠的多器官病变

期刊:Blood
影响因子:23.1
doi:10.1182/blood-2015-01-625707
Arumugam Paritha I, Mullins Eric S, Shanmukhappa Shiva Kumar, Monia Brett P, Loberg Anastacia, Shaw Maureen A, Rizvi Tilat, Wansapura Janaka, Degen Jay L, Malik Punam
细胞生物学
发表日期：2015
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Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies

以豚尾猕猴为模型研究慢病毒载体介导的血红蛋白病基因治疗的长期安全性

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1038/mtm.2014.55
Kiem, Hans-Peter; Arumugam, Paritha I; Burtner, Christopher R; Fox, Catherine F; Beard, Brian C; Dexheimer, Phillip; Adair, Jennifer E; Malik, Punam
微生物学
基因治疗
发表日期：2014
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