文献库，生知库 | 链接生命科学的每一步

Takii Takemasa, Yamada Hiroyuki, Motozono Chihiro, Yamasaki Sho, Torrelles Jordi B, Turner Joanne, Kimishima Aoi, Asami Yukihiro, Ohara Naoya, Hida Shigeaki, Hayashi Hidetoshi, Onozaki Kikuo

细胞生物学

Human

焦亡

发表日期：2025

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PurA is the main target of aurodox, a type III secretion system inhibitor

PurA是Aurodox（一种III型分泌系统抑制剂）的主要靶点。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2322363121

Watanabe, Yoshihiro; Haneda, Takeshi; Kimishima, Aoi; Kuwae, Asaomi; Suga, Takuya; Suzuki, Takahiro; Iwabuchi, Yoshiharu; Honsho, Masako; Honma, Sota; Iwatsuki, Masato; Matsui, Hidehito; Hanaki, Hideaki; Kanoh, Naoki; Abe, Akio; Asami, Yukihiro; Ōmura, Satoshi

发表日期：2024

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Comparative genomics reveals insight into the phylogeny and habitat adaptation of novel Amycolatopsis species, an endophytic actinomycete associated with scab lesions on potato tubers

比较基因组学揭示了新型内生放线菌属（Amycolatopsis）物种的系统发育和栖息地适应性，该物种与马铃薯块茎上的疮痂病病斑有关。

期刊:Frontiers in Plant Science

影响因子:4.8

doi:10.3389/fpls.2024.1346574

Wannawong, Thippawan; Mhuantong, Wuttichai; Macharoen, Pipat; Niemhom, Nantawan; Sitdhipol, Jaruwan; Chaiyawan, Neungnut; Umrung, Sarinna; Tanasupawat, Somboon; Suwannarach, Nakarin; Asami, Yukihiro; Kuncharoen, Nattakorn

发育与干细胞

发表日期：2024

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In vitro and in vivo activities of KSP-1007, a broad-spectrum inhibitor of serine- and metallo-β-lactamases, in combination with meropenem against carbapenem-resistant Gram-negative bacteria

KSP-1007（一种广谱丝氨酸和金属β-内酰胺酶抑制剂）与美罗培南联合用药对耐碳青霉烯类革兰氏阴性菌的体外和体内活性研究

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.01602-23

Takemoto, Koji; Nakayama, Ryo; Fujimoto, Koichi; Suzuki, Yumiko; Takarabe, Yukiko; Honsho, Masako; Kitahara, Sachiko; Noguchi, Yoshihiko; Matsui, Hidehito; Hirose, Tomoyasu; Asami, Yukihiro; Hidaka, Jun; Sunazuka, Toshiaki; Hanaki, Hideaki

发表日期：2024

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Binding Mode-Based Physicochemical Screening Method Using d-Ala-d-Ala Silica Gel and Chemical Modification Approach to Facilitate Discovery of New Macrolactams, Banglactams A and B, from Nonomuraea bangladeshensis K18-0086

利用d-Ala-d-Ala硅胶结合结合模式的理化筛选方法和化学修饰方法，促进从Nonomuraea bangladeshensis K18-0086中发现新的大环内酰胺类化合物Banglactams A和B。

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.4c00145

Kimishima, Aoi; Suzuki, Yuki; Kosaka, Shohei; Honsho, Masako; Honma, Sota; Tsutsumi, Hayama; Inahashi, Yuki; Watanabe, Yoshihiro; Nakashima, Takuji; Asami, Yukihiro; Iwatsuki, Masato

发表日期：2024

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Synthesis and biological evaluation of burnettiene A derivatives enabling discovery of novel fungicide candidates

伯氏烯A衍生物的合成及生物学评价，助力发现新型杀菌剂候选物

期刊:Journal of Pesticide Science

影响因子:1.8

doi:10.1584/jpestics.D24-014

Kimishima, Aoi; Nishitomi, Atsuka; Tsuruoka, Iori; Honsho, Masako; Negami, Sota; Honma, Sota; Sakai, Katsuyuki; Tokiwa, Toshiyuki; Kojima, Hiroki; Nonaka, Kenichi; Fuji, Shin-Ichi; Chinen, Takumi; Usui, Takeo; Asami, Yukihiro

发表日期：2024

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Synthesis and biological evaluation of MS-347a derivatives against plant pathogenic fungi based on a strategy of laeA gene introduction

基于laeA基因导入策略的MS-347a衍生物的合成及其对植物病原真菌的生物学评价

期刊:Journal of Pesticide Science

影响因子:1.8

doi:10.1584/jpestics.D24-035

Kimishima, Aoi; Honma, Sota; Kimishima, Atsushi; Nishitomi, Atsuka; Honsho, Masako; Wasuwanich, Paul; Kojima, Hiroki; Tokiwa, Toshiyuki; Sugawara, Akihiro; Araki, Yasuko; Takahashi, Tadashi; Chinen, Takumi; Usui, Takeo; Fuji, Shin-Ichi; Ito, Kotaro; Asami, Yukihiro

Design and Synthesis of d-Ala-d-Ala Silica Gel for a Binding Mode-Based Physicochemical Screening Method

基于结合模式的理化筛选方法的d-Ala-d-Ala硅胶的设计与合成

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.3c03837

Kimishima, Aoi; Suzuki, Yuki; Kosaka, Shohei; Honsho, Masako; Honma, Sota; Sakai, Kazunari; Tsutsumi, Hayama; Inahashi, Yuki; Watanabe, Yoshihiro; Iwatsuki, Masato; Asami, Yukihiro; Nakashima, Takuji

发表日期：2023

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CRM646-A, a Fungal Metabolite, Induces Nucleus Condensation by Increasing Ca(2+) Levels in Rat 3Y1 Fibroblast Cells

真菌代谢产物CRM646-A通过增加大鼠3Y1成纤维细胞中Ca(2+)水平诱导细胞核浓缩

期刊:Journal of Microbiology and Biotechnology

影响因子:3.1

doi:10.4014/jmb.1908.08043

Asami, Yukihiro; Kim, Sun-Ok; Jang, Jun-Pil; Ko, Sung-Kyun; Kim, Bo Yeon; Osada, Hiroyuki; Jang, Jae-Hyuk; Ahn, Jong Seog

Mechanism of the natural product moracin-O derived MO-460 and its targeting protein hnRNPA2B1 on HIF-1α inhibition

天然产物moracin-O衍生的MO-460及其靶蛋白hnRNPA2B1对HIF-1α抑制的机制

期刊:Experimental and Molecular Medicine

影响因子:12.9

doi:10.1038/s12276-018-0200-4

Soung, Nak-Kyun; Kim, Hye-Min; Asami, Yukihiro; Kim, Dong Hyun; Cho, Yangrae; Naik, Ravi; Jang, Yerin; Jang, Kusic; Han, Ho Jin; Ganipisetti, Srinivas Rao; Cha-Molstad, Hyunjoo; Hwang, Joonsung; Lee, Kyung Ho; Ko, Sung-Kyun; Jang, Jae-Hyuk; Ryoo, In-Ja; Kwon, Yong Tae; Lee, Kyung Sang; Osada, Hiroyuki; Lee, Kyeong; Kim, Bo Yeon; Ahn, Jong Seog

发表日期：2019

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Mycobacterium tuberculosis bacillus induces pyroptosis in human lung fibroblasts.

结核分枝杆菌可诱导人肺成纤维细胞发生焦亡

PurA is the main target of aurodox, a type III secretion system inhibitor

PurA是Aurodox（一种III型分泌系统抑制剂）的主要靶点。

Comparative genomics reveals insight into the phylogeny and habitat adaptation of novel Amycolatopsis species, an endophytic actinomycete associated with scab lesions on potato tubers

比较基因组学揭示了新型内生放线菌属（Amycolatopsis）物种的系统发育和栖息地适应性，该物种与马铃薯块茎上的疮痂病病斑有关。

In vitro and in vivo activities of KSP-1007, a broad-spectrum inhibitor of serine- and metallo-β-lactamases, in combination with meropenem against carbapenem-resistant Gram-negative bacteria

KSP-1007（一种广谱丝氨酸和金属β-内酰胺酶抑制剂）与美罗培南联合用药对耐碳青霉烯类革兰氏阴性菌的体外和体内活性研究

Binding Mode-Based Physicochemical Screening Method Using d-Ala-d-Ala Silica Gel and Chemical Modification Approach to Facilitate Discovery of New Macrolactams, Banglactams A and B, from Nonomuraea bangladeshensis K18-0086

利用d-Ala-d-Ala硅胶结合结合模式的理化筛选方法和化学修饰方法，促进从Nonomuraea bangladeshensis K18-0086中发现新的大环内酰胺类化合物Banglactams A和B。

Synthesis and biological evaluation of burnettiene A derivatives enabling discovery of novel fungicide candidates

伯氏烯A衍生物的合成及生物学评价，助力发现新型杀菌剂候选物

Synthesis and biological evaluation of MS-347a derivatives against plant pathogenic fungi based on a strategy of laeA gene introduction

基于laeA基因导入策略的MS-347a衍生物的合成及其对植物病原真菌的生物学评价

Design and Synthesis of d-Ala-d-Ala Silica Gel for a Binding Mode-Based Physicochemical Screening Method

基于结合模式的理化筛选方法的d-Ala-d-Ala硅胶的设计与合成

CRM646-A, a Fungal Metabolite, Induces Nucleus Condensation by Increasing Ca(2+) Levels in Rat 3Y1 Fibroblast Cells

真菌代谢产物CRM646-A通过增加大鼠3Y1成纤维细胞中Ca(2+)水平诱导细胞核浓缩

Mechanism of the natural product moracin-O derived MO-460 and its targeting protein hnRNPA2B1 on HIF-1α inhibition

天然产物moracin-O衍生的MO-460及其靶蛋白hnRNPA2B1对HIF-1α抑制的机制