日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Turning on Protein Function Inhibited by DNA Aptamers Employing a Covalent DNA-Binding Protein

利用共价DNA结合蛋白激活被DNA适配体抑制的蛋白质功能

期刊:ACS Nanoscience Au
影响因子:6.3
doi:10.1021/acsnanoscienceau.5c00143
Kanazu, Takeru; Komiya, Erika; Miura, Daimei; Tsukakoshi, Kaori; Ikebukuro, Kazunori; Yamazaki, Tomohiko; Asano, Ryutaro
发表日期：2026
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Creation of an Engineered Oxygen-Insensitive L-Glutamate Oxidase for the Application of Electrochemical L-Glutamate Sensors

构建一种对氧不敏感的工程化L-谷氨酸氧化酶，用于电化学L-谷氨酸传感器的应用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27062831
Hatada, Mika; Takamatsu, Shouhei; Asano, Ryutaro; Ikebukuro, Kazunori; Tsugawa, Wakako; Sode, Koji
发表日期：2026
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A Unique Insertion Loop Facilitates Tight NAD(+) Binding in Nicotinoprotein: Insights from In Vitro Loop Engineering and In Silico Studies

独特的插入环促进烟酸蛋白与NAD(+)的紧密结合：来自体外环工程和计算机模拟研究的启示

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27052367
Xue, Houcheng; Yanase, Takumi; Okuda-Shimazaki, Junko; Kawai, Haruka; Miura, Daimei; Asano, Ryutaro; Ikebukuro, Kazunori; Sode, Koji; Tsugawa, Wakako
发表日期：2026
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Design of a prodrug bispecific antibody masked by a functional molecule for lymphocyte activation for cancer therapy

设计一种由功能分子掩蔽的前药双特异性抗体，用于激活淋巴细胞以治疗癌症。

期刊:Journal of Biological Engineering
影响因子:6.5
doi:10.1186/s13036-025-00517-9
Miura, Daimei; Kato, Yuki; Yasunaga, Masahiro; Kumagai, Izumi; Asano, Ryutaro
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Construction and Characterization of a Novel Direct Electron Transfer Type Enzymatic Sensor Using Spermidine Dehydrogenase

利用亚精胺脱氢酶构建和表征一种新型直接电子转移型酶传感器

期刊:Biosensors-Basel
影响因子:5.6
doi:10.3390/bios15100681
Tong, Sheng; Yaegashi, Yuki; Fukushi, Mao; Yanase, Takumi; Okuda-Shimazaki, Junko; Asano, Ryutaro; Ikebukuro, Kazunori; Nagata, Madoka; Sode, Koji; Tsugawa, Wakako
发表日期：2025
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Immunological synapse formation as a key mechanism in T cell-dependent bispecific antibody-mediated immune activation and cytotoxicity.

免疫突触形成是 T 细胞依赖性双特异性抗体介导的免疫激活和细胞毒性的关键机制

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-025-04036-w
Nakamura Rikuto, Tsumura Ryo, Anzai Takahiro, Asano Ryutaro, Yasunaga Masahiro
细胞生物学
发表日期：2025
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Transient analysis and engineering of bacterial metabolic pathways using cell-penetrating peptide-peptide nucleic acid conjugates

利用细胞穿透肽-肽核酸缀合物对细菌代谢途径进行瞬态分析和工程改造

期刊:Microbial Cell Factories
影响因子:4.9
doi:10.1186/s12934-025-02909-4
Kawabuchi, Yugo; Kobayashi, Shunichi; Yu, Jaeyoung; Kasai, Gota; Kobe, Miku; Suo, Rei; Itoi, Shiro; Sode, Koji; Muraoka, Takahiro; Asano, Ryutaro; Mori, Tetsushi
微生物学
细胞生物学
代谢
发表日期：2025
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Engineered single chain variable fragments (scFvs) with improved pH-dependent kinetics for use in continuous biosensor applications

工程化单链可变片段（scFv）具有改进的pH依赖性动力学，可用于连续生物传感器应用

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra02051d
Wilson, Ellie D; Probst, David; Hamasaki, Mai; Oda, Miho; Kochar, Varun; Xu, Qianming; Tanaka, Ayumi; Suzuki, Hirobumi; Asano, Ryutaro; Sode, Koji
发表日期：2025
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Evaluation of an anti-CD3 VHH and construction of an anti-CD3/anti-EGFR bispecific tandem VHH as a cancer cell targeting drug construct

评估抗CD3 VHH并构建抗CD3/抗EGFR双特异性串联VHH作为靶向癌细胞的药物载体

期刊:Biochemistry and Biophysics Reports
影响因子:2.2
doi:10.1016/j.bbrep.2025.102015
Asanuma, Takuya; Ding, Peiwei; Kato, Yuki; Nakanishi, Takeshi; Asano, Ryutaro; Makabe, Koki
CD3
EGFR
细胞生物学
肿瘤
EGF
肿瘤免疫
发表日期：2025
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Exploration and Application of DNA-Binding Proteins to Make a Versatile DNA-Protein Covalent-Linking Patch (D-Pclip): The Case of a Biosensing Element

利用DNA结合蛋白构建多功能DNA-蛋白共价连接贴片（D-Pclip）：以生物传感元件为例

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.3c12668
Komiya, Erika; Takamatsu, Shouhei; Miura, Daimei; Tsukakoshi, Kaori; Tsugawa, Wakako; Sode, Koji; Ikebukuro, Kazunori; Asano, Ryutaro
发表日期：2024
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