日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Resistance mechanisms and therapeutic strategies of CDK4 and CDK6 kinase targeting in cancer

癌症中 CDK4 和 CDK6 激酶靶向治疗的耐药机制和治疗策略

Asciolla, James J; Wu, Xuewei; Adamopoulos, Christos; Gavathiotis, Evripidis; Poulikakos, Poulikos I

Specification of positional identity in forebrain organoids

前脑类器官中位置身份的规范

Gustav Y Cederquist, James J Asciolla, Jason Tchieu, Ryan M Walsh, Daniela Cornacchia, Marilyn D Resh, Lorenz Studer

Hedgehog Acyltransferase Promotes Uptake of Palmitoyl-CoA across the Endoplasmic Reticulum Membrane

Hedgehog 酰基转移酶促进内质网膜对棕榈酰辅酶 A 的吸收

James J Asciolla, Marilyn D Resh

In Vitro Analysis of Hedgehog Acyltransferase and Porcupine Fatty Acyltransferase Activities

刺猬酰基转移酶和豪猪脂肪酰基转移酶活性的体外分析

Asciolla, James John; Rajanala, Kalpana; Resh, Marilyn D

An in vitro fatty acylation assay reveals a mechanism for Wnt recognition by the acyltransferase Porcupine.

体外脂肪酰化分析揭示了酰基转移酶 Porcupine 识别 Wnt 的机制

Asciolla James J, Miele Matthew M, Hendrickson Ronald C, Resh Marilyn D

Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors

线粒体分裂是 RAS 诱导转化的必要条件,也是致癌 MAPK 通路抑制剂的靶点

Madhavika N Serasinghe, Shira Y Wieder, Thibaud T Renault, Rana Elkholi, James J Asciolla, Jonathon L Yao, Omar Jabado, Kyle Hoehn, Yusuke Kageyama, Hiromi Sesaki, Jerry E Chipuk

Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance

抗凋亡 BCL-2 蛋白控制 B-RAF(V600E) 抑制后的细胞结果,并可作为降低耐药性的靶向药物

M N Serasinghe, D J Missert, J J Asciolla, S Podgrabinska, S Y Wieder, S Izadmehr, G Belbin, M Skobe, J E Chipuk